[Significance of the stool occult blood test in patients with thrombotic disease under treatment with low dose aspirin].

We encountered lower gastrointestinal bleeding in 16 patients taking a low dose of aspirin and examined the effect of low aspirin dose on the stool occult blood test in 49 thrombotic patients (mean: 76.7 +/- 9.6 years old) including 39 with cerebral infarction, 8 with ischemic heart disease and 2 with atrial fibrillation.

Influence of aging on the carcinogen-induced protein kinase activity in rat liver cell nuclei.

A carcinogen-induced increase in a protein kinase activity was found in cell nuclei of rat liver. The enzyme was extracted from isolated nuclei with a hypotonic buffer, retained to an anion-exchange column, eluted with 0.15 M NaCl containing solution and to be measured for the activity with casein as the substrate, showing a nature of a casein kinase.