Publications by authors named "Akio Fujiya"
Introduction: The aim of this study was to describe a simple technique for the implantation of toric intraocular lenses (IOLs) with increased stability during ophthalmic viscosurgical device (OVD) removal.
Methods: The technique was performed on 20 eyes with 20 patients (mean age: 77.9 ± 9.
Patients with incomplete posterior vitreous detachment, especially with vitreomacular adhesion, can form a macular hole after Nd-YAG laser capsulotomy. It is recommended to inform the risk of forming a macular hole before Nd-YAG laser treatment.
View Article and Find Full Text PDFPurpose: To report outer retinal abnormalities evaluated using high-resolution imaging modalities in a patient with Danon disease.
Methods: Case report.
Results: A 26-year-old woman, diagnosed with Danon disease based on genetic testing, was referred to our department for further evaluation of ocular findings.
Unsaturated Aldehyde Acrolein Promotes Retinal Glial Cell Migration.
Invest Ophthalmol Vis Sci
October 2019
Article Synopsis
- - The study aimed to examine how acrolein, an unsaturated aldehyde, affects the movement of Müller glial cells in the retina.
- - Results showed that while high levels of acrolein reduced cell viability, moderate concentrations boosted cell migration and increased production of the protein CXCL1, which is linked to cell movement.
- - The findings suggest that acrolein enhances Müller glial cell migration by increasing CXCL1 levels, which is relevant in conditions like proliferative diabetic retinopathy (PDR).
Purpose: To investigate sequential post-operative thickness changes in inner and outer retinal layers in eyes with an idiopathic macular hole (MH).
Methods: Retrospective case series. Twenty-four eyes of 23 patients who had received pars plana vitrectomy (PPV) for the closure of MH were included in the study.
Article Synopsis
- The study aimed to analyze the level of vascular endothelial growth factor (VEGF) in subretinal fluid from a patient with vasoproliferative retinal tumors (VPRTs).
- The patient, a 30-year-old male, had VPRTs following a long-term retinal detachment and was treated with various surgical interventions, including an injection of bevacizumab.
- Results showed that the VEGF level in the patient's subretinal fluid (12,997.9 pg/mL) was significantly higher than that in patients with rhegmatogenous retinal detachment (average 2.1 pg/mL), suggesting that VEGF production increases in VPRTs and indicating that anti-VEGF therapy could be
Purpose: To investigate postoperative thickness changes in the retinal layers in eyes with epiretinal membrane (ERM). Correlations between these changes and visual outcomes were also examined.
Methods: Retrospective review of 25 eyes (24 patients) that had undergone pars plana vitrectomy for ERM and had a postoperative follow-up period ≥6 months.
Purpose: To examine whether vasoproliferative retinal tumors (VPRTs) express vascular endothelial growth factor and respond to intravitreal bevacizumab injection.
Methods: Retrospective interventional case series. Intravitreal bevacizumab 1.
Aim: To quantitatively evaluate the time course of macular choroidal blood flow velocity in acute central serous chorioretinopathy (CSC).
Methods: This retrospective observational case series included 21 eyes of 20 patients (17 men, 3 women; mean age, 53.0 years) with treatment-naïve acute CSC.
Purpose: Previous studies have reported that astaxanthin (AXT) has antioxidative and anti-inflammatory effects in addition to its ability to shorten blood transit times. As laser speckle flowgraphy (LSFG) can noninvasively visualize the hemodynamics of the choroidal circulation, we used the technique to evaluate whether continuous ingestion of 12 mg of AXT per day could increase quantitative blood flow velocity.
Methods: In this randomized, double-blind, placebo-controlled study, we examined 20 healthy volunteers who ingested 12 mg AXT or placebo capsules over a 4-week period.