Publications by authors named "Akio Akahane"

Subcutaneous implantation type central venous ports(CV ports)are used in chemotherapy. Here, we prospectively examined the frequency of CV port-related infections when the disinfectant was changed from 10% povidone iodine to 1% chlorhexidine ethanol or 70% ethanol. The subjects were patients with malignant tumors, who had newly been implanted with CV ports.

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Purpose: The purpose of this study was to show the effectiveness of combining intra-arterial infusion and systemic chemotherapy with concurrent radiotherapy for treatment of stage IV mandibular gingival cancer.

Materials And Methods: A total of 23 patients with mandibular gingival cancer were treated with either docetaxel by intra-arterial infusion followed by systemic chemoradiotherapy with cisplatinum and 5-fluorouracil as a monthly regimen, or with docetaxel and cisplatinum by intra-arterial infusion followed by systemic chemoradiotherapy with 5-fluorouracil as a weekly or biweekly regimen. Tumor responses, locoregional control, overall survival, disease-specific survival, and adverse events were evaluated.

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Article Synopsis
  • The study focused on evaluating the characteristics of infections related to central venous ports (CVPs) in patients with malignant tumors, using microbiological assessments before and after CVP placement.
  • Out of 59 patients enrolled, a 5.1% rate of CVP-related infections was found, with no definitive bloodstream infections, and more colonization observed in subclavian CVP sites compared to forearm sites.
  • The findings suggest that while skin colonization is more common in subclavian placements, it was not definitively linked to infection risk, highlighting the need for proper CVP maintenance.
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Purpose: This study was designed to compare central venous ports (CVP) from two different routes of venous access-the subclavian vein and arm vein-in terms of safety for patients with head and neck cancer (HNC).

Methods: Patients with HNC who underwent image-guided implantations of CVPs were retrospectively evaluated. All CVPs were implanted under local anesthesia.

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