The homologous Arabidopsis MRS2/MGT/CorA-type Mg channels, AtMRS2-10 and AtMRS2-1 exhibit different aluminum transport activity.

Magnesium (Mg) plays a critical role in many physiological processes. The AtMRS2/MGT family, which consists of nine Arabidopsis genes (and two pseudo-genes) belongs to a eukaryotic subset of the CorA superfamily of divalent cation transporters. AtMRS2-10 and AtMRS2-1 possess the signature GlyMetAsn sequence conserved in the CorA superfamily; however, they have low sequence conservation with CorA.