Publications by authors named "Akinjide R Akintunde"

Article Synopsis
  • - The text discusses the use of constitutive models that combine different materials to predict how biological tissues respond to stress, ensuring their behavior aligns with prior experimental data.
  • - It introduces an advanced method using Bayesian analysis to improve parameter estimation in these models, particularly focused on the mechanical response of the murine patellar tendon.
  • - The findings indicate that while certain models reveal significant insights into tissue integrity, the Freed-Rajagopal model shows better parameter tracking compared to others, highlighting the importance of using comprehensive data over averaged results for accurate analysis.
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Although the underlying mechanisms of pelvic organ prolapse (POP) remain unknown, disruption of elastic fiber metabolism within the vaginal wall extracellular matrix (ECM) has been highly implicated. It has been hypothesized that elastic fiber fragmentation correlates to decreased structural integrity and increased risk of prolapse; however, the mechanisms by which elastic fiber damage may contribute to prolapse are poorly understood. Furthermore, the role of elastic fibers in normal vaginal wall mechanics has not been fully ascertained.

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Tendon injuries are common to all ages. Injured tendons typically do not recover full functionality. The amount and organization of tendon constituents dictate their mechanical properties.

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