[Metastatic tumors of the retroperitoneal space].

In 22 patients retroperitoneal nonorganic tumors, considered to be primary, proved to be metastatic. Prior to surgery the character of neoplasms was recognized only in 4 patients. Due to unwarranted efforts of "radical" removal of tumors 2 of 4 patients died.

[Proliferation kinetics of NK/Ly tumor cells after single and fractionated irradiation with fast electrons].

With single irradiation, the inhibition of tumor cell division and DNA synthesis was more pronounced than with fractionation irradiation. In fractionated schedules, the dose increase per fraction, and the interval prolongation between fractions, with decrease of the number of fractions (within the same time of irradiation), enhanced the effect of radiation. Yield of pahologic mitoses and extent of morphologic injury of cells was less expressed with fractionated irradiation and did not depend on the schedule of fractionation of the total dose.

[Influence of fast electrons on the nucleic acid level and the biosynthsis of RNA in cells of the ascites tumor NK/Ly and the spleen of tumor-bearing mice].

The results of investigations on total nucleic acids content and RNA turnover in the cells of tumor NK/Ly and of the spleen in tumor-bearing mice after single exposure to fast electrons are described. In every case the irradiation results in reliable changes of parameters under study. The pattern of changes in nucleic acids content and turnover in the spleen after the exposure to fast electrons is in a good agreement with the available data concerning the influence of x- and y-radiation.