Publications by authors named "Akilandeswari Balachandran"
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Synopsis of recent research by authors named "Akilandeswari Balachandran"
- Akilandeswari Balachandran's research predominantly focuses on the use of antisense oligonucleotides and aptamer-based therapies in targeting cancer-related proteins, specifically the epidermal growth factor receptor and nucleolin, to enhance treatment efficacy against various malignancies.
- Key findings reveal that splice-switching antisense oligonucleotides can modulate gene expression to inhibit cancer cell proliferation and that targeting specific proteins like HMGA can lead to significant inhibition of retinoblastoma cell growth.
- Balachandran's work also highlights the therapeutic potential of microRNAs in brain cancers and the application of chimeric aptamer-DNAzyme constructs for targeted cancer cell therapy, suggesting innovative strategies for deploying molecular therapies in oncology.
