Publications by authors named "Akilan Meiyappan"

Article Synopsis
  • Accurate forecasts improve public health responses to seasonal influenza, with 26 teams providing predictions for hospital admissions in 2021-22 and 2022-23.
  • Six out of 23 models performed better than the baseline in 2021-22, while 12 out of 18 models did so in 2022-23, with the FluSight ensemble being highly ranked in both seasons.
  • Despite its accuracy, the FluSight ensemble and other models struggled with longer forecast periods, especially during times of rapid change in influenza patterns.
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Accurate forecasts can enable more effective public health responses during seasonal influenza epidemics. Forecasting teams were asked to provide national and jurisdiction-specific probabilistic predictions of weekly confirmed influenza hospital admissions for one through four weeks ahead for the 2021-22 and 2022-23 influenza seasons. Across both seasons, 26 teams submitted forecasts, with the submitting teams varying between seasons.

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CD8 T cells constitute an essential compartment of the adaptive immune system. During immune responses, naı̈ve T cells become functional, as they are primed with their cognate determinants by the antigen presenting cells. Current methods of identifying activated CD8 T cells are laborious, time-consuming and expensive due to the extensive list of required reagents.

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