Publications by authors named "Akilah Ali"

Caregivers provide support to persons who might otherwise require placement in long-term care facilities. Approximately one in five U.S.

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Article Synopsis
  • SARS-CoV-2 Omicron variants may affect how well vaccines work and how long immunity lasts, prompting a study on the effectiveness of the Pfizer-BioNTech vaccine among different age groups in the U.S.
  • From January 16 to May 28, 2022, researchers analyzed COVID-19 infection rates relative to vaccination status across multiple jurisdictions, tracking declines in vaccine effectiveness over time.
  • Results showed lower vaccine protection in younger age groups, particularly those aged 5-11, and a general decline in effectiveness for all ages as time since vaccination increased, indicating a need to monitor waning immunity during the Omicron surge.
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  • The CDC has been tracking SARS-CoV-2 variants, particularly the Omicron variant, through national genomic surveillance since December 2020, with a report summarizing trends from January 2022 to May 2023.
  • Throughout this period, various Omicron descendant lineages, such as BA.1.1, BA.2, and BA.5, rose and fell in prevalence, often correlating with spikes in COVID-19 cases.
  • By May 2023, the variant XBB.1.5 dominated, underscoring the ongoing evolution of variants and the necessity for genomic surveillance to aid in vaccine and therapeutic strategies.
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Purpose: The Metropolitan Atlanta Developmental Disabilities Surveillance Program tracks autism spectrum disorder (ASD) in selected counties within Georgia as part of the Autism and Developmental Disabilities Monitoring (ADDM) Network. ADDM Network analyses have historically found a higher prevalence of ASD in areas of higher socioeconomic status.

Methods: We linked 2018 data from Centers for Disease Control and Prevention's Social Vulnerability Index (SVI) to two Metropolitan Atlanta Developmental Disabilities Surveillance Program counties by census tract, grouped census tracts into tertiles representing low, medium, and high social vulnerability, and calculated ASD prevalence for each tertile, overall and by each of four SVI themes.

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While some studies have previously estimated lives saved by COVID-19 vaccination, we estimate how many deaths could have been averted by vaccination in the US but were not because of a failure to vaccinate. We used a simple method based on a nationally representative dataset to estimate the preventable deaths among unvaccinated individuals in the US from May 30, 2021 to September 3, 2022 adjusted for the effects of age and time. We estimated that at least 232,000 deaths could have been prevented among unvaccinated adults during the 15 months had they been vaccinated with at least a primary series.

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On September 1, 2022, CDC recommended an updated (bivalent) COVID-19 vaccine booster to help restore waning protection conferred by previous vaccination and broaden protection against emerging variants for persons aged ≥12 years (subsequently extended to persons aged ≥6 months).* To assess the impact of original (monovalent) COVID-19 vaccines and bivalent boosters, case and mortality rate ratios (RRs) were estimated comparing unvaccinated and vaccinated persons aged ≥12 years by overall receipt of and by time since booster vaccination (monovalent or bivalent) during Delta variant and Omicron sublineage (BA.1, BA.

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Article Synopsis
  • * The Alpha variant, which emerged in late 2020, featured a S-gene deletion leading to a testing anomaly called S-gene target failure (SGTF).
  • * Recently, the XBB.1.5 sublineage with S-gene target presence (SGTP) has emerged, showing rapid growth in the northeastern U.S. during the dominance of the Omicron BA.5 variants exhibiting SGTF.
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Effective methods to assess mental disorders in children are necessary for accurate prevalence estimates and to monitor prevalence over time. This study assessed updates of the tic disorder and attention-deficit/hyperactivity disorder (ADHD) modules of the Diagnostic Interview Schedule for Children, Version 5 (DISC-5) that reflect changes in diagnostic criteria in the Diagnostic and Statistical Manual of Mental Disorders (Fifth edition, DSM-5). The DISC-5 tic disorder and ADHD parent- and child-report modules were compared to expert clinical assessment for 100 children aged 6-17 years (40 with tic disorder alone, 17 with tic disorder and ADHD, 9 with ADHD alone, and 34 with neither) for validation.

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Previous reports of COVID-19 case, hospitalization, and death rates by vaccination status indicate that vaccine protection against infection, as well as serious COVID-19 illness for some groups, declined with the emergence of the B.1.617.

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Problem/condition: Autism spectrum disorder (ASD).

Period Covered: 2018.

Description Of System: The Autism and Developmental Disabilities Monitoring Network is an active surveillance program that estimates ASD prevalence and monitors timing of ASD identification among children aged 4 and 8 years.

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Problem/condition: Autism spectrum disorder (ASD).

Period Covered: 2018.

Description Of System: The Autism and Developmental Disabilities Monitoring (ADDM) Network conducts active surveillance of ASD.

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