Publications by authors named "Akila Subramanian"
Mid-trimester preterm premature rupture of membranes is a rare complication of pregnancy associated with significant maternal and fetal risks. The ensuing prolonged oligohydramnios can lead to fetal pulmonary hypoplasia. In addition, there is an increased risk of miscarriage, preterm birth, and chorioamnionitis, contributing to septic morbidity in the mother-baby dyad.
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- This study investigates crown-rump length (CRL) discordance in twin pregnancies, which is defined as a ≥10% difference in measurements, to see if it's linked to higher risks of fetal abnormalities and adverse outcomes.
- The objective is to determine the correlation between CRL discordance and conditions like aneuploidy, structural anomalies, and perinatal complications, while also assessing the effectiveness of cell-free DNA screening in these cases.
- The research involves analyzing data from a previous multicenter study on twin pregnancies, comparing those with CRL discordance to those without, and examining the rates of adverse outcomes and screening performance.