Publications by authors named "Akiko Saito-Moriya"
Impact of asparaginase discontinuation on outcomes of children with acute lymphoblastic leukaemia receiving the Japan Association of Childhood Leukaemia Study ALL-02 protocol.
Hisashi Ishida Toshihiko Imamura Yasuhisa Tatebe Takashi Ishihara Kimiyoshi Sakaguchi Akiko Saito-Moriya
Br J Haematol
June 2023
Article Synopsis
- * The Japan Association of Childhood Leukaemia Study ALL-02 protocol introduced additional chemotherapies and increased corticosteroid use to manage lower treatment intensity when asparaginase is discontinued.
- * Despite improvements, such as reduced allergy rates, the study showed that discontinuing asparaginase remains a significant risk factor for event-free survival, suggesting the need for ongoing refinement in its use.