Synopsis of recent research by authors named "Akiko Namba"
- Akiko Namba's research primarily focuses on the pathogenesis of neuroinflammatory diseases, including multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS), with particular emphasis on the roles of specific biomarkers and therapeutic agents in these conditions.
- In recent studies, Namba has identified the exacerbating effect of food additives like succinate on autoimmune encephalitis and highlighted the role of Sema4A in Th17 cell-mediated neuroinflammation, suggesting its potential as a therapeutic target for MS.
- Namba's work also investigates the protective effects of various pharmacological agents such as febuxostat and the prostacyclin analog ONO-1301-MS, demonstrating their capacity to mitigate neurodegeneration and oxidative stress in animal models of ALS and other neuroinflammatory disorders.