Publications by authors named "Akiko Kudo"
Article Synopsis
- This study focuses on the importance of predicting the time to renal replacement therapy (RRT) for patients at a high risk of end-stage kidney disease.
- Researchers developed and tested machine learning models using data from chronic kidney disease (CKD) patients at Oita University Hospital, comparing the accuracy of these models to traditional methods based on the rate of estimated glomerular filtration rate (eGFR) decline.
- The machine learning approach demonstrated moderate predictive accuracy (R of 0.60), significantly outperforming the conventional method, which had an extremely low accuracy (R of -17.1), highlighting the potential for machine learning to improve CKD treatment predictions.
We herein report a 43-year-old woman with Buerger's disease who presented with nephrotic syndrome, renal dysfunction, and mild hypertension. A kidney biopsy revealed focal segmental glomerulosclerosis (FSGS), but there were no findings associated with frequent secondary FSGS or a history of long-term hypertension. A small focal renal infarction was seen on Tc-dimercaptosuccinic acid renal scintigraphy, suggesting that FSGS was due to renal microinfarction associated with Buerger's disease.
View Article and Find Full Text PDFA 70-year-old woman was diagnosed with multiple myeloma in 2014. She achieved complete remission (CR) after bortezomib, cyclophosphamide, dexamethasone (VCD) therapy and lenalidomide, dexamethasone (Rd) therapy; however, she relapsed in 2017. Although she achieved second CR by carfilzomib, dexamethasone (Kd) therapy, serum creatinine levels increased with urinary protein after 17 courses of Kd therapy.
View Article and Find Full Text PDFObjective: Sleeve gastrectomy (SG) has been reported to decrease blood pressure (BP), although the reason has not been revealed. The present study aimed to establish the reason why SG decreases BP.
Methods: Male Sprague-Dawley rats were subjected to surgical (sham operation or SG) and dietary interventions (fed a normal diet or high-fat diet ad libitum or fed by pair-feeding [PF]).
At present, there is no set strategy for the treatment of patients with colorectal cancer subsequent to the failure of standard treatment, other than the use of regorafenib (RGR) and TAS-102. The best order in which to use these drugs, and their safety and efficacy in combination with other drugs, are currently under investigation. It has been reported that RGR has a resensitizing effect on tumors that have previously failed to respond to anticancer drugs; this makes it a promising salvage therapy for colorectal cancer.
View Article and Find Full Text PDFAn 18-year-old man was admitted to our hospital due to gross hematuria and proteinuria after a marathon race. Contrast-enhanced CT showed no remarkable findings. His gross hematuria and proteinuria disappeared with- out treatment.
View Article and Find Full Text PDFBackground: The aim of this study was to confirm and compare the efficacy of fluvoxamine (the only licensed SSRI for treatment for OCD in Japan) and behavior therapy in treating Japanese patients with OCD. In addition, we investigated predictors of these treatments.
Methods: Thirty-one outpatients meeting the DSM-III-R criteria for OCD without any axis I disorder were randomly assigned to one of three treatment conditions: BT (behavior therapy +/- pill placebo), FLV [autogenic training (a psychological placebo for OCD) +/- fluvoxamine] and control group [autogenic training (psychological placebo) +/- pill placebo] for 12 weeks of treatment.