Publications by authors named "Akiko Kanda"
Article Synopsis
- This study investigates the success rates of second kidney transplants (TX2) compared to first ones (TX1) in Japanese patients, as data on TX2 outcomes are limited.
- Using data from 33 TX2 among 898 kidney transplants performed from 2010 to 2019, researchers applied survival analysis methods to assess death-censored graft survival (DCGS) and overall survival (OS) rates.
- The results indicated that while TX2 has comparable short-term survival rates to TX1, there were no significant differences found, suggesting that TX2 is a viable option for patients needing a second transplant.
L-Pipecolic acid is utilized as a vital component of specific chemical compounds, such as immunosuppressive drugs, anticancer reagents, and anesthetic reagents. We isolated and characterized a novel L-aminoacylase, N-acetyl-L-pipecolic acid-specific aminoacylase (LpipACY), from Pseudomonas sp. AK2.
View Article and Find Full Text PDFObjectives: Our aim was to investigate effects of surgery on living donors' body composition and clarify factors related to it.
Materials And Methods: We evaluated preoperative computed tomography images of 335 living kidney donors (127 men, 209 women) to calculate 3 body composition parameters and changes with aging by sex: (1) skeletal muscle mass, quantified by skeletal muscle index; (2) fat distribution, calculated by visceral adipose tissue/subcutaneous adipose tissue ratio; and (3) muscle quality, quantified by intramuscular adipose tissue content. Thereafter, with pre- and postoperative computed tomography images from 75 living kidney donors (25 men, 50 women) after hand-assisted laparoscopic donor nephrectomy, we compared pre- and postoperative body composition changes.
Purpose: To assess an embryo's ability to develop into a good-quality blastocyst during the early-cleavage stage using time-lapse imaging and the oxygen consumption rate.
Methods: In total, 942 zygotes had their oxygen consumption rates measured. In total, 282 zygotes were assessed by using time-lapse imaging.
Article Synopsis
- - The study assessed the effects of cyclophosphamide (CPA) on oocyte fertilization and embryo growth in mice, finding that higher CPA doses (≥400 mg/kg) significantly reduced the number of viable oocytes and fertility rates.
- - Despite the decrease in the number of metaphase II oocytes and fertilization rates after high CPA doses, embryos that were fertilized grew normally, with development features resembling those of control group embryos.
- - One month post-CPA treatment, both the number of retrievable oocytes and their capability to develop into blastocysts were restored to levels comparable to the control group, indicating a recovery of reproductive potential.
Immunoenzymometric assay for recombinant methioninase in biological fluids.
J Pharm Biomed Anal
October 2002
Immunoassay for recombinant methioninase (rMETase), an anti-cancer agent, in biological sample was developed. Antisera were produced by immunizing rabbits with rMETase. The antisera were evaluated using radioiodine-labeled rMETase and good antisera for sensitive immunoassay were obtained.
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