Publications by authors named "Akiko Futatsugi"

Article Synopsis
  • Cholesterol efflux capacity (CEC) is an important marker for cardiovascular disease risk and is influenced by high-density lipoprotein (HDL) functionality and concentration.
  • A study found that neonates (less than 28 days old) have significantly lower CEC levels compared to older participants, indicating not only lower HDL concentration but also impaired HDL functionality.
  • The research suggests that the differences in CEC/stCEC ratios in neonates and infants are linked to specific HDL lipid compositions, while in children over one year old, these ratios do not correlate with HDL lipid markers.
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Background And Objectives: Allergic transfusion reactions (ATRs) and febrile non-haemolytic transfusion reactions (FNHTRs) are common, although their mechanisms remain unclear. Immunoglobulin E (IgE)-mediated type I hypersensitivity may be involved in the pathogenesis of ATR. A basophil activation test (BAT) may help elucidate this process.

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Article Synopsis
  • Parenteral nutrition (PN) is crucial for children undergoing specific medical procedures, such as hematopoietic stem cell transplantation (HSCT), but its temporary interruptions pose unclear risks.
  • A study analyzed 22 children who needed PN during HSCT, focusing on blood glucose levels after adjusting for a temporary pause in PN to administer medication, finding that higher glucose infusion rates increased hypoglycemia risk.
  • The results emphasize the need for careful monitoring and precautions in children with higher glucose infusion rates during these interruptions to avoid complications.
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Lipoprotein-X (LP-X) in cholestatic jaundice causes abnormal reaction in assays for low-density lipoprotein-cholesterol, but the effects on other test items are unknown. Here, we report an infant with biliary atresia showing abnormal reaction in total serum protein assay using the biuret method, and lipoprotein-X (LP-X) was then detected. In this 11-month-old female infant, jaundice was observed at 2 months old, and a diagnosis of biliary atresia was made.

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