Publications by authors named "Akiho Iwashita"

Article Synopsis
  • Primary biliary cholangitis (PBC) is a chronic liver disease linked to high cholesterol, but it's generally not thought to increase the risk of coronary artery disease, so pre-transplant heart screening isn't standard practice.
  • A case study of a 40-year-old woman with PBC who had a liver transplant revealed that she experienced acute coronary syndrome (ACS) shortly after surgery, leading to the discovery of significant blockages in her coronary arteries.
  • The case suggests that patients with PBC and severe dyslipidemia could be at higher risk for heart issues post-transplant, indicating a need for preoperative heart evaluations in these high-risk individuals.
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Enucleation is the process whereby the nucleus is extruded from the erythroblast during late stage mammalian erythropoiesis. However, the specific signaling pathways involved in this process remain unclear. To better understand the mechanisms underlying erythroblast enucleation, we investigated erythroblast enucleation using both the spleens of adult mice with phenylhydrazine-induced anemia and mouse fetal livers.

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