Publications by authors named "Akihiro Saitsu"

Article Synopsis
  • * Results show that older adults with a high fracture risk (FRAX® score > 15%) have significantly higher 4-HNE levels compared to those with low risk, suggesting a relationship between oxidative stress and bone health.
  • * The findings support the idea that 4-HNE could serve as a useful clinical marker to assess fracture risk due to oxidative stress in older individuals.
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Background: Malpositioning of the acetabular cup during total hip arthroplasty (THA) can lead to complications. Robotic surgery and navigation techniques aim to address this issue, but there is limited evidence regarding which method can achieve better clinical outcomes. Therefore, this network meta-analysis (NMA) aimed to compare the efficacy of various navigation methods.

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Article Synopsis
  • The study aimed to assess the impact of untreated medial meniscal ramp lesions (MMRLs) on tendon grafts following anterior cruciate ligament (ACL) reconstruction using a pig model.
  • A total of 17 pigs were divided into two groups: one with untreated MMRLs and another with intact medial meniscus, and after 12 weeks, their specimens were tested for differences in structural properties and histology.
  • Although there were no significant differences in mechanical performance between the two groups, the group with untreated MMRLs showed considerably worse histological scores, indicating tissue deterioration post-surgery.
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Purpose: A history of fractures involving the distal radius, proximal humerus, spine, and hip may be associated with the incidence of subsequent hip fractures in older people. However, a comprehensive summary of this association using a rigorous methodology is lacking. Our objective was to systematically review the literature and examine the association between four major osteoporotic fractures and subsequent hip fractures in individuals aged ≥ 50 years.

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Background Achilles tendinopathy is a common ankle disorder in both the general population and athletes. This condition can alter the mechanical characteristics of the Achilles tendon (AT) by decreasing tendon stiffness. Achilles tendinopathy is primarily treated conservatively; however, few monitoring tools exist for evaluating the condition of the AT.

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A 72-year-old female patient with a fixed valgus knee deformity due to a Schatzker type V tibial plateau fracture treated with bilateral locking plates 8 years ago was admitted to our clinic with complaints of chronic pain and knee instability when walking. Radiographs revealed Kellgren-Lawrence Classification grade 4 knee osteoarthritis and 20.5° of valgus knee deformity.

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Background: This study aimed to morphologically and histologically examine whether pig is useful as models for rotator cuff tear (RCT).

Methods: The morphology of the scapula and humerus bones was evaluated by taking X-ray and three-dimensional computed tomography (3D CT) scans of the right shoulders of five female pigs (age: 4 months). The rotator cuff (RC) footprint at the humeral insertion of these was observed and its shape was measured.

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Article Synopsis
  • Frozen shoulder (FS) is a painful condition affecting mainly those aged 40-60, and while physical therapy (PT) is often recommended, some patients still experience long-term pain and dysfunction.
  • This study involved 102 patients with severe FS, comparing the effectiveness of manipulation under anesthesia (MUB) versus PT over one year, measuring pain, range of motion, and overall shoulder function at multiple follow-ups.
  • Results showed that MUB significantly improved pain and shoulder function compared to PT, with lower associated costs ($1375 for MUB vs $2751 for PT) and better quality of life outcomes.
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Background: A frozen shoulder (FS) is characterized by pain and limited range of motion (ROM). Although physical assessment of ROM is important for diagnosing and staging FS, ROM cannot be accurately assessed in clinical practice because of pain and muscle contraction. This study aimed to measure changes in shoulder joint ROM before and after anesthesia (ΔROM) in patients with FS and investigate the factors affecting these changes.

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Purpose: To investigate whether the biomechanical properties of the healed superficial medial collateral ligament (sMCL) repaired by augmentation vary depending on the material properties of the suture augmentation.

Methods: In 8 of 10 porcines (16 hindlimbs), the sMCL was detached from the femoral attachment using a scalpel under intubated general anesthesia. sMCL repair was performed using an ultra-high-molecular-weight polyethylene (UHMWPE) tape for the right hindlimbs and polyester tape (PE) for the left hindlimbs.

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Background: This study compared the clinical results of fracture stems and conventional stems using the same glenoid component in reverse shoulder arthroplasty for proximal humerus fractures in the elderly.

Methods: This retrospective study included 35 patients who underwent Grammont-type reverse shoulder arthroplasty for proximal humerus fractures from 2014 to 2020. The average age at surgery was 79.

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A 66-year-old Japanese woman presented with upper abdominal pain and nausea after having eaten several rice cakes. An abdominal CT scan showed retained rice cakes in the stomach, which led to intestinal obstruction three days later.

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Purpose: Osteopenia typically presents low bone mineral density (BMD) and has recently been reported as a prognostic factor in various cancers. However, the prognostic value of osteopenia in digestive tract cancers remains to be defined. We aimed to review the prognostic value of preoperative osteopenia in patients with digestive cancers.

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The pathophysiology of sarcopenia is complex and must be further explored. While metabolic acidosis may be a risk factor for sarcopenia, it remains unclear whether acidic urine is related to sarcopenia. The purpose of the present study was to investigate the association between sarcopenia and urine pH in the elderly.

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