Effects of fibronectin on osteoinductive capability of fresh iliac bone marrow aspirate in posterolateral spinal fusion in rabbits.

Study Design: A rabbit model of posterolateral intertransverse process spine arthrodesis was used.

Objective: To assess the osteogenic potential of hydroxyapatite (HA) sticks soaked with marrow and resultant strength in spinal fusion and effects of various biologic agents, in particular fibronectin (FN) on the strength.

Summary Of Background Data: Mesenchymal stem cells (MSCs) contained in marrow can differentiate into cells constituting bone, cartilage, muscles and fat.