Slow progressive popliteal artery insufficiency after neglected proximal tibial physeal fracture: a case report.

Popliteal artery injury is most commonly associated with high-energy trauma, which is easily diagnosed upon initial physical examination. However, in some situations, the diagnosis of arterial injury is delayed because of slow progression of arterial insufficiency, which may lead to limb amputation. We report a rare case of popliteal arterial occlusion with the presence of arterial pulses during initial assessment, resulting from a neglected proximal ibial physis fracture.

Promotion of skeletal muscle repair in a rat skeletal muscle injury model by local injection of human adipose tissue-derived regenerative cells.

Human adipose tissue-derived regenerative cells (ADRCs) can be isolated easily and aseptically from unwanted subcutaneous fat without culturing. ADRCs have been used in clinical cosmetic therapy. In addition, they are expected to be an attractive and feasible source of cell-based therapies in regenerative medicine.

In vivo bioluminescence imaging of magnetically targeted bone marrow-derived mesenchymal stem cells in skeletal muscle injury model.

The purpose of this study is to clarify the kinetics of transplanted mesenchymal stem cells (MSCs) in rat skeletal muscle injury model and the contribution of the magnetic cell delivery system to muscle injury repair. A magnetic field generator was used to apply an external magnetic force to the injury site of the tibia anterior muscle, and 1 × 10(6) MSCs labeled with ferucarbotran-protamine complexes, which were isolated from luciferase transgenic rats, were injected into the injury site. MSCs were injected with and without an external magnetic force (MSC M+ and MSC M- groups, respectively), and phosphate-buffered saline was injected into injury sites as a control.