Publications by authors named "Akihiro Kushiyama"

Article Synopsis
  • This study evaluated how different oral anticoagulants (OACs) affect activated clotting time (ACT) during catheter ablation procedures for atrial fibrillation, involving 554 patients across five types of OACs.
  • Dabigatran led to a faster and more stable achievement of target ACT compared to rivaroxaban and apixaban, while edoxaban and warfarin showed similar results to dabigatran in terms of time to reach target ACT.
  • The research found no significant differences in periprocedural complications among the five OAC groups, highlighting that dabigatran might be the most efficient option under continuous use in clinical practice.
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  • - The study evaluated a new technique for atrial fibrillation (AF) ablation that uses intracardiac echocardiography (ICE) to reduce radiation exposure compared to traditional methods, involving 233 patients with the new strategy and 223 patients under conventional protocols.
  • - Findings showed that while the initial time to start ablation was slightly longer with the new method, the overall procedure time and radiation exposure were significantly reduced, leading to similar rates of in-hospital complications.
  • - Although the new strategy improved safety in terms of radiation, the rate of patients remaining free from arrhythmias after two years did not show significant differences compared to the conventional approach.
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Introduction: There is a paucity of data on the influence of low body weight on clinical outcomes in patients with acute venous thromboembolism (VTE).

Materials And Methods: The COMMAND VTE registry is a multicenter cohort study enrolling 3027 consecutive patients with acute symptomatic VTE. The current study population consisted of 2778 patients with available body weight value, who were divided into 2 groups; 1705 patients with lower body weight (≤60 kg) and 1073 patients with higher body weight (>60 kg).

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Background: This study aimed to evaluate the effect of the initial aortic valve replacement (AVR) strategy relative to a conservative strategy on long-term outcomes stratified by age among asymptomatic patients with severe aortic stenosis (AS).

Methods and results: Among 1,808 asymptomatic severe AS patients in the CURRENT AS registry, there were 1,166 patients aged ≥75 years (initial AVR: n=124, and conservative: n=1,042), and 642 patients with age <75 years (initial AVR: n=167, and conservative: n=475). Median follow-up interval was 1,280 (interquartile range [IQR]: 1,012-1,611) days, and 1461 (IQR: 1,132-1,886) days in patients aged ≥ and <75 years, respectively.

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Article Synopsis
  • Ablation index (AI) is a new measurement for evaluating the quality of tissue lesions created during radiofrequency (RF) catheter ablation, but its reliability still needs validation.
  • In this study, researchers tested lesions in pig hearts by applying RF at various angles and power levels, finding that AI correlated well with lesion size (depth, width, volume).
  • The results indicated that AI was most reliable at specific contact angles and power settings, showing decreased lesion size with lower contact angles and that higher RF power didn’t always yield larger lesions.
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  • Electroanatomic voltage mapping (EAVM) was conducted on the left atrium of 44 patients during both sinus rhythm (SR) and atrial fibrillation (AF) to assess its feasibility for detecting low-voltage areas (LVA).
  • A significant difference in the proportions of LVA was observed between SR and AF rhythms, particularly at lower voltage cutoff values, with a strong correlation noted when using a cutoff of 0.2 mV.
  • The findings suggest that EAVM during AF is feasible and that a cutoff of 0.2 mV is optimal for detecting LVA, but results might be less reliable in patients with larger LVA.
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We report 2 cases of severe perioperative coronary artery spasm in thoracic aortic surgery. Case 1 was a 72-year-old male with a distal arch aneurysm of 74 mm while case 2 was a 74-year-old male with acute type A aortic dissection. We performed thoracic aortic repair (total arch replacement and ascending aorta replacement) under moderately hypothermic circulatory arrest (25 °C) and selective cerebral perfusion in both cases.

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