Clinical outcomes of open and closed management after surgical treatments in patients with medication-related osteonecrosis of the jaw.

Context And Purpose: To achieve success following surgical treatment of MRONJ, complete wound closure has been considered necessary; open wound management has not been generally recommended. Therefore, various closure techniques using local flaps have been reported. However, these techniques often increase surgical invasiveness, and there is minimal evidence regarding whether complete wound closure is preferable to open wound management following surgical treatment of MRONJ.

Intravascular papillary endothelial hyperplasia in the mandible: a case report.

Intravascular papillary endothelial hyperplasia (IPEH) is histopathologically characterized by papillary proliferation of vascular endothelial cells. IPEH in the mandible is very rare, such that only four affected patients have been described in the English-language medical literature. Thus, there is a poor understanding of the pathogenesis and clinical features of IPEH in the mandible.

Adenosquamous carcinoma development as a recurrence of squamous cell carcinoma in the oral floor: A case report.

Rationale: Oral adenosquamous carcinoma (ASC) is rare and its origins are controversial. We here present a patient with oral ASC that developed after surgery for oral squamous cell carcinoma (SCC).

Patient Concerns: A 70-year-old man with SCC on the oral floor underwent surgical resection.

Multiple oral ulcers caused by incorrect use of oral bisphosphonate in a patient with dementia: A case report.

It is not widely known that incorrect use of oral bisphosphonates (BPs), such as chewing the medication, can cause oral ulcers. An 83-year-old woman with dementia was referred to our clinic with multiple oral ulcers. Blood and histopathological examinations were inconclusive.

Malignant external otitis following radiotherapy for oral cancer: A case report.

Rationale: Although an ototoxicity is well-known as adverse event of the radiotherapy, it is not widely known that immunosuppressed patients who underwent radiotherapy in head and neck region have risk of malignant external otitis.

Patient Concerns: A 68-year-old man with diabetes, who had been diagnosed as intraosseous squamous cell carcinoma of the right mandible, underwent surgical resection. He received a total of 60 Gy/30Fr postoperative radiation.