Quality of the calcium-enriched mixture apical plug in simulated apexification model; Effect of different mixing and placement methods.

Background: Presence of voids at root canal wall‒apical seal material interface gives rise to the entrapment of toxins and microorganisms, which might have a relationship with post treatment disease. The present study was carried out to evaluate the effect of different mixing (manual and ultrasonic) and placement (manual and manual in association with indirect ultrasonic) methods of Calcium-enriched Mixture (CEM) cement on the number and dimensions of voids in the apical plug in simulated apexification models.

Material And Methods: A total of 80 human maxillary central incisors with mature apices were selected.