Unilateral vitritis in an immunocompetent individual - A rare presentation of ocular toxoplasmosis.

Ocular toxoplasmosis is the leading cause of infectious retinochoroiditis in both adults and children. It is caused by the obligate intracellular parasite, Toxoplasma gondii. It is a common cause of posterior uveitis and focal retinitis, typically seen in immunocompetent individuals as a primary infection or in immunocompromised individuals as reactivation of latent infection.

A rare case of tamoxifen induced bilateral optic neuritis.

Tamoxifen, an oral medication that blocks estrogen activity, is frequently prescribed for the treatment of advanced breast cancer and as an additional therapy following surgical removal of early stage disease. A 45-year-old female with a history of breast carcinoma treated with tamoxifen presented with sudden onset bilateral visual impairment for 4 days. On ocular examination, the patient exhibited optic disc edema with hyperemia and bilateral anterior pathway defects in visual evoked potentials.

CerviXpert: A multi-structural convolutional neural network for predicting cervix type and cervical cell abnormalities.

Objectives: Cervical cancer, a leading cause of cancer-related deaths among women globally, has a significantly higher survival rate when diagnosed early. Traditional diagnostic methods like Pap smears and cervical biopsies rely heavily on the skills of cytologists, making the process prone to errors. This study aims to develop CerviXpert, a multi-structural convolutional neural network designed to classify cervix types and detect cervical cell abnormalities efficiently.

Rhinoplasty and YouTube: A Cross-Sectional Study to Assess the Quality, Dependability, and Reliability of Videos on Rhinoplasty.

Introduction: Rhinoplasty, also referred to as a nose job or a reconstruction of the nose, is a surgical procedure that alters and reconstructs the nose for aesthetic or functional purposes. With the emergence of social media and modern internet accessibility, YouTube has gained popularity among users of all ages. Despite this, the accuracy and credibility of these videos and the information they include could be cause for concern.

Phytochemical characterization, antioxidant and antibacterial activities of crude extracts of and .

The aim of this study was to determine the phytochemical profile, antibacterial and antioxidant activities of crude aqueous leaf extracts of and . The predominant components present in these crude extracts of test plants identified using gas chromatography-mass spectrometry (GC-MS) analysis in both plant extracts were phytochemicals including flavonoids, tannins, terpenoids, and phenols. The antibacterial activity of crude extracts of these plants against bacterial pathogens including sp.

Outcome of transcanalicular laser dacryocystorhinostomy with endonasal augmentation in acute versus post-acute dacryocystitis.

Objective: To study the outcomes of transcanalicular laser dacryocystorhinostomy (TCL-DCR) with endonasal augmentation in acute versus post-acute dacryocystitis and compare it with external DCR in post-acute settings.

Methods: A prospective, randomised study was conducted in 90 adult cases of Acute dacryocystitis. All the patients were started on systemic antibiotics and a 4 mm × 4 mm osteotomy was created using TCL-DCR.

Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice.

Inhibition of Notch signaling in macrophages is known to reduce inflammation, however, its role in regulating vascular hyporeactivity in sepsis is unknown. Thus we aimed to evaluate the effect of sepsis on vascular Notch signaling. Polymicrobial sepsis was induced by caecal ligation and puncture (CLP) in mice.

Early marriage among Syrian refugees in Jordan: exploring contested meanings through ethnography.

Early marriage remains a central concern among reproductive and sexual rights advocates worldwide. Mainstream researchers have often focused on the negative effects of early marriage on young women, presenting them as powerless victims of social and cultural traditions. Yet the voices and perceptions of young women remain strongly absent in many studies on early marriage.

Calcium signaling cascades differentially regulate PGF-induced myometrial contractions in water buffaloes (Bubalus bubalis).

This study unravels the differential involvement of calcium signaling pathway(s) in PGF-induced contractions in myometrium of nonpregnant (NP) and pregnant buffaloes. Compared to the myometrium of pregnant animals, myometrium of NP buffaloes was more sensitive to PGF as manifested by changes in mean integral tension (MIT) and tonicity. In the presence of nifedipine, myometrial contraction to PGF was significantly attenuated in both NP and pregnant uteri; however, mibefradil and NNC 55-0396 produced inhibitory effects only in uterus of pregnant animals, thus suggesting the role of extracellular Ca influx through nifedipine-sensitive L-type Ca-channels both in NP and pregnant, but T-type Ca channels seem to play a role only during pregnancy.

Effect of Incorporation of Nano-Oxides on Color Stability of Maxillofacial Silicone Elastomer Subjected to Outdoor Weathering.

Purpose: The aim of this study was to evaluate the effect of incorporation of two compositions of nano-oxides on color stability of intrinsically colored maxillofacial silicone elastomer subjected to outdoor weathering.

Materials And Methods: Ninety Cosmesil M511 silicone elastomer specimens were fabricated. The control group was incorporated with intrinsic coloring agents (umber, brown, yellow), group A was incorporated with intrinsic coloring agents and nanosized titanium oxide (TiO ), and group B was incorporated with intrinsic coloring agents and nanosized zinc oxide (ZnO).

Case report: association of combined nonarteritic anterior ischemic optic neuropathy (NAION) and obstruction of cilioretinal artery with overdose of Viagra.

Aims: We report on a case of combined nonarteritic anterior ischemic optic neuropathy (NAAION) and cilioretinal artery occlusion resulting from misuse of sildenafil citrate (Viagra Pfizer Pharmaceuticals, New York, NY).

Design: This is an observational case report.

Methods: A 54-year-old white man developed blindness in his left eye after an overdose of Viagra.