Rhythmicity in testicular melatonin and its correlation with the dynamics of spermatogenic cells in an annual reproductive cycle of Clarias batrachus under natural photo-thermal conditions.

Melatonin, the pineal hormone, is synthesized and secreted rhythmically in accordance with various environmental cues especially photo-thermal conditions. The reproductive physiology of seasonal breeders is synchronized with the surroundings by melatonin as a neuroendocrine mediator to acts as an important factor in fish reproduction. However, the data on the participation of melatonin in male reproduction and the putative interaction with the process of spermatogenesis in fish is scarce till date.

In silico study to unravel molecular networking of melatonin in the regulation of gametogenesis.

Melatonin, a pineal hormone, has potential role on steroidogenesis, growth and maturation of sperm and ovum during gametogenesis. The possible use of this indolamine as an antioxidant in the production of good quality gametes opens up a new area of current research. Nowadays, a large number of reproductive dysfunctions like infertility and failure in fertilization due to gametic malformations are major concern worldwide.