Publications by authors named "Akari Yagita"

Treatment outcomes for inoperable advanced non-small cell lung cancer have improved in recent years. However, information on coexisting haematological tumours is lacking. The present patient was a 65-year-old woman with stage IVA lung adenocarcinoma.

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Article Synopsis
  • - The study investigates the impact of freezing duration on cell damage during transbronchial lung cryobiopsy, which is used to diagnose lung diseases by providing larger, less crushed tissue samples compared to traditional methods.
  • - Jurkat cells were frozen for varying durations (2-6 seconds) and tested for cell viability and marker expression; results indicated that longer freezing resulted in more viable cells, especially those farther from the freezing probe.
  • - Cryobiopsy showed promise for accurate diagnoses, yielding over 90% live cells and consistent cytological results in a clinical case involving a patient suspected of malignant lymphoma, suggesting its effectiveness for further lung condition evaluations.
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We describe the case of a 36-year-old man diagnosed with human immunodeficiency virus (HIV) following prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. The patient had a complication of pneumocystis pneumonia. Upon initiating highly active antiretroviral therapy, we monitored HIV RNA levels, CD4+ T-cell count, SARS-CoV-2 viral load, and IgG antibodies against SARS-CoV-2.

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Introduction: Sotorasib is a crucial therapeutic agent for patients with non-small cell lung cancer (NSCLC) harboring the KRAS p.G12C mutation. Despite its efficacy, the relationship between blood sotorasib concentrations and side effects remains largely unexplored.

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