Prognostic significance of Ki67 during neoadjuvant chemotherapy in primary unresectable ovarian cancer.

Aim: The purpose of this study was to investigate whether the Ki67 values were associated with survival for predicting prognosis in patients with advanced ovarian cancer receiving neoadjuvant chemotherapy (NACT).

Methods: Among 17 patients treated with NACT, 13 patients were available for tissue samples from matched pre- and post-therapy tissues. Ki67 scores were transformed to a logarithmic scale for the statistical analyses.

Laparoscopic Surgery for Ovarian Epidermoid Cyst with Preservation of Ovarian Function.

Ovarian epidermoid cyst, an extremely rare tumor occurring mostly in older females, is lined by mature stratified squamous epithelium and distinguishable from mature teratoma by the absence of skin adnexae and other tissues. In imaging, these tumors resemble solid tumors, necessitating most patients to undergo oophorectomy to verify malignancy. We herein present the case of an ovarian epidermoid cyst in a pregnant woman who underwent laparoscopic cystectomy after delivery with preserved ovarian function.

Eucommia ulmoides extracts prevent the formation of advanced glycation end products.

Proteins non-enzymatically react with reducing sugars to form advanced glycation end-products (AGEs), resulting in the induction of protein denaturation. Because the levels of AGE increase with age and are elevated in age-related diseases, such as diabetes and atherosclerosis, the intake of compound(s) that inhibit the formation of AGEs by daily meal may represent a potential strategy for preventing age-related diseases. In this study, we measured the inhibitory effects of several Eucommia ulmoides extracts on the formation of AGEs, N(ε)-(carboxymethyl)lysine (CML) and N(ω)-(carboxymethyl)arginine (CMA).