The attenuation of doxorubicin-induced testicular toxicity with improved testicular histoarchitecture of mice by the bioactive compounds in leaves: Experimental and computational studies.

Doxorubicin, as an antibiotic causes toxicity in human tissues through the generation of oxidant species; however, (Solanaceae) is ethnopharmacologically and scientifically reported to possess antidotal activities. This study was designed to validate the antidotal potency of the plant's bioactive compounds on rats' testes following induction with doxorubicin through the evaluation of oxidative stress markers, lipid peroxidation indices, testes' histological sections, and profiling of the plant's bioactive compounds against some proteins. The collection and preparation of the plant extract, testicular toxicity induction, seminal analysis, assay of testosterone and oxidative stress markers, lipid peroxidation profiling, histomorphological studies, retrieval of catalase, superoxide dismutase, and glutathione peroxidase from PDB, GC-MS, ADME, and docking analyses followed standard protocols.

Health risk assessment of lead, cadmium, heavy metals and metalloids in residential paint flakes from indoor wall surfaces.

Paint components pose risky metals like lead, cadmium, arsenic, and mercury that endanger occupants, mainly children and pregnant women. To assess the levels and health risks of 14 metals in paint flakes from indoor walls of residential houses in four states in South-western Nigeria. Flaked paints were collected from 144 houses where children reside.

The antimalarial profiling of 's herbal formulation attenuated biochemical alterations and improved hepatocytes' histoarchitecture in -infected mice.

Plasmodium parasite causes malaria and affects the biochemical, physiological, and histoarchitecture of the hepatocytes and blood. The resultant effect leads to alterations in the metabolic activities of the liver, erythrocytes, as well as the buffer system. Therefore, we investigated the antiplasmodial activity, histomorphological studies of the hepatocytes and alterations in biochemical parameters in infected mice administered with the herbal formulation of aqueous extracts of stem bark and leaves.

Risk assessment and origin of metals in chicken meat and its organs from a commercial poultry farm in Akwa Ibom state, Nigeria.

Contamination of chicken with metals is on the increase, despite its known attendant health risks to human consumers. The study aimed to evaluate the concentration of some metals in various organs of chicken, their sources, and the health risks they pose to human consumers. Samples of liver, meat, gizzard, borehole water, soil, diets, and droppings were investigated for the presence of some metals (Cr, Co, Mn, Zn, Al, As, Cd, Ni, and Hg), and their sources using principal component analysis (PCA).

Improvement of biotic nitrate reduction in constructed photoautotrophic biofilm-soil microbial fuel cells.

The biotic nitrate reduction rate in freshwater ecosystems is typically constrained by the scarcity of carbon sources. In this study, 'two-chambers' - 'two-electrodes' photoautotrophic biofilm-soil microbial fuel cells (P-SMFC) was developed to accelerate nitrate reduction by activating in situ electron donors that originated from the soil organic carbon (SOC). The nitrate reduction rate of P-SMFC (0.

The interplay of hematite and photic biofilm triggers the acceleration of biotic nitrate removal.

The soil-water interface is replete with photic biofilm and iron minerals; however, the potential of how iron minerals promote biotic nitrate removal is still unknown. This study investigates the physiological and ecological responses of photic biofilm to hematite (FeO), in order to explore a practically feasible approach for in-situ nitrate removal. The nitrate removal by photic biofilm was significantly higher in the presence of FeO (92.

Spice-Induced Metal Contamination and Microbiological Risk Assessment of Instant Noodles Prepared for Human Consumption.

With the rising worries of potential metal contamination in cooked noodles, this study aimed at unravelling, for the first time, the possible source of metal contamination in cooked noodles. Noodles cooked with full spices (CWFS), cooked with half spices (CWHS), cooked with quarter spices (CWQS), and cooked with no spices (CWNS: control) and their spices were analysed for metals using inductively coupled plasma-atomic emission spectrometry. The microbiological quality of the noodles was also evaluated.

Susceptibility of Cd availability in microplastics contaminated paddy soil: Influence of ferric minerals and sulfate reduction.

The combined contamination of cadmium (Cd) and microplastics (MPs) in paddy soil always occurred, while its influence on Cd availability remained unclear. This study investigated the Cd availability in Cd-MPs co-contaminated paddy soil in consideration of both ferric minerals and sulfate reduction under flooding conditions. The presence of MPs resulted in a higher Cd releasing risk, as represented by the increase in the available Cd and decrease in Fe-Mn oxide-bound Cd contents, especially on the 7th and 14th days based on the sequential extraction results.

Reduced arsenic availability in paddy soil through Fe-organic ligand complexation mediated by bamboo biochar.

The reuse of arsenic (As)-contaminated paddy fields is a global challenge because long-term flooding would result in As release due to the reductive dissolution of iron minerals. Biochar amendment is a common and effective remediation technique for As-contaminated paddy soil. However, the literature is still lacking in systematic research on the function of biochar in controlling the complexation of released dissolved organic matter (DOM) and iron oxides and its synergistic impact on the availability of As in flooded paddy soil.

Hormonal and haematological biomarkers as indicators of stress induced by Diuron herbicide toxicity on Clarias gariepinus (Burchell, 1822) sub-adults.

Diuron is a globally used herbicide for weed control but has anti-androgenic effects on androgens (testosterone and androstenedione), antagonist effects on thyroid hormone signaling, and haematological effects due to their biotransformation in fish. Endocrine-disrupting biomarkers such as thyroid hormones, sex hormones, and haematological indices of Clarias gariepinus sub-adults exposed to sub-lethal diuron concentrations were studied over a 28-day period. C.

Deterioration of the quality of packaged potable water (bottled water) exposed to sunlight for a prolonged period: An implication for public health.

The exposure of bottled water to sunlight leaches heavy metals into the water, thereby deteriorating its quality and this informed the study. Three plastic bottle brands (n = 100 per brand) were exposed to sunlight for different durations. The leaching of contaminants was exposure duration dependent.

Heavy metal co-resistance with antibiotics amongst bacteria isolates from an open dumpsite soil.

Heavy metal co-resistance with antibiotics appears to be synergistic in bacterial isolates via similar mechanisms. This synergy has the potential to amplify antibiotics resistance genes in the environment which can be transferred into clinical settings. The aim of this study was to assess the co-resistance of heavy metals with antibiotics in bacteria from dumpsite in addition to physicochemical analysis.

Public health threats of heavy metals due to the consumption of Achachatina marginata (African Giant Land Snail) from a partially remediated site in Ikot Ada Udo, Akwa Ibom State, South-South Nigeria.

The risk of oral intake of metals from the ingestion of contaminated Achachatina marginata was carried-out. Snail samples (n = 48) were hand-picked, preserved in ice, then analyzed for zinc (Zn), nickel (Ni), chromium (Cr) using inductively coupled plasma-atomic emission spectrometry (ICP-AES, Yobin Yvon JY-24), then cadmium (Cd), lead (Pb) using graphite furnace atomic absorption spectrometry (GF-AAS, 4110 ZL PerkinElmer). The mean levels of metals in snail from each sampling point were higher compared to the control site.