Publications by authors named "Akaninyene I Noah"
Article Synopsis
- The study examined the link between fetal sex (specifically female) and hypertensive disorders of pregnancy (HDP) among 43,737 singleton pregnancies, considering various maternal characteristics.
- Results showed a marginal association between female fetal sex and superimposed preeclampsia, particularly in women over 35, those who are obese, and parous women.
- The findings suggest that female fetuses may be more influenced by certain maternal factors when it comes to the risk of developing superimposed preeclampsia, while no significant links were found for other hypertensive disorders.
Objective: Per- and polyfluoroalkyl substances (PFAS) alter immune function increasing infectious diseases risk. We examined the relationship between PFAS and chlamydia.
Methods: A total of 3965 nonpregnant adults ages 18-39 years from the National Nutrition Examination Survey 2003-2016 cycles were included.
Background: In singleton pregnancies, fetal sexual dimorphism has been observed in hypertensive disorders of pregnancy, particularly preeclampsia, a morbid syndrome that increases the risk of adult-onset cardiovascular disease for mothers and their offspring. However, few studies have explored the effect of fetal sex on hypertensive disorders of pregnancy among twin pregnancies.
Methods: We conducted a retrospective cohort study of 1032 twin pregnancies between 2011 and 2022 using data from a perinatal database that recruits participants from 3 hospitals in Houston, TX.
Article Synopsis
- The study investigates the impact of fetal sex on hypertensive disorders of pregnancy (HDP) in twin pregnancies, focusing on conditions like preeclampsia, using data from over 1,000 twin pregnancies in Houston between 2011 and 2022.
- Researchers categorized twin pregnancies by fetal sex (female/female, male/male, and female/male) and found that female/male twins had a higher risk of preterm preeclampsia compared to female/female pairs.
- The findings suggest a link between fetal sex pairs and HDP, particularly preterm preeclampsia, highlighting the need for further research into the biological factors involved.
To explore the association between acculturation among foreign-born (FB) women, gestational diabetes (GDM) and GDM-associated adverse birth outcomes, we conducted a retrospective cohort study of 34,696 singleton pregnancies from Houston, TX, between 2011 and 2022. FB women (n = 18,472) were categorized based on years of residence in US (0-5, 6-10, and > 10 years), while US-born women (n = 16,224) were the reference group. A modified Poisson regression model determined the association between acculturative level and GDM within the entire cohort and stratified by race/ethnicity.
View Article and Find Full Text PDFFetal-sex-specific changes to placental immunity and metabolism occur in response to obesity. Few studies have determined if fetal sex interacts with maternal characteristics to alter risk of gestational diabetes mellitus (GDM). Among 43,727 singleton pregnancies, we examined the association between male fetal sex and GDM using log-binomial logistic regression to calculate relative risks (RR) and 95% confidence intervals (CI).
View Article and Find Full Text PDFProblem: Interferon epsilon (IFNε) is a unique type I IFN that is expressed in response to sex steroids. Studies suggest that type I IFNs regulate inflammation-induced preterm birth (PTB), but no study has examined the role of IFNε in human pregnancy.
Method Of Study: We used stored vaginal swabs between 8 and 26 weeks of gestation from the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS) biobank and measured IFNε by enzyme-linked immunosorbent assay (ELISA).