Publications by authors named "Akane Sonobe"
Cholesteatoma has an altered microbiota with a higher abundance of species.
Laryngoscope Investig Otolaryngol
December 2022
Article Synopsis
- - The study aimed to compare the microbiota of cholesteatomas and chronic suppurative otitis media (COM) to identify potential pathogens linked to cholesteatoma phenotypes.
- - Analysis of surgical specimens showed significant differences in bacterial composition between cholesteatomas and COM, with certain bacteria being more prevalent in cholesteatomas.
- - Findings indicate that coagulase-negative staphylococci (CoNS) could serve as biomarkers for cholesteatomas, and their abundance was positively correlated with the size of the cholesteatoma, suggesting their role in disease progression.