Publications by authors named "Akane Satake"
Introduction: Uterine adenomyosis is a benign disorder in which endometrial glands and stroma are present within the myometrium. There have been several case reports of cerebral infarction associated with adenomyosis, but their clinical characteristics, optimal treatment, and prognosis have not been systematically reviewed.
Methods: A case of cerebral infarction with adenomyosis is reported, and a comprehensive systematic literature search using the PubMed database was conducted.
We report a 77-year-old woman with a thymoma, anti-LGI1antibody associated encephalitis (LGI1 encephalitis), and MG accompanied by positive anti-acetylcholine receptor antibodies (AchR Ab) and anti-titin antibodies (titin Ab). She was treated with thymomectomy followed by immunosuppressive therapy, which resulted in immediate amelioration of motor weakness and gradual improvement of cognitive impairment over the next two years. LGI1 Ab were positive at two months after thymomectomy, followed by negative conversion demonstrated on 1 year examination.
View Article and Find Full Text PDFDentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant neurodegenerative disorder characterized by slowly progressive cerebellar ataxia. Previously, autonomic symptoms or dysfunction have not been reported. To evaluate subclinical autonomic dysfunction regarding thermoregulatory function in SCA, we recorded sympathetic outflow to skin in a DRPLA patient confirmed by genetic analysis.
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- A 44-year-old woman presented with mild walking difficulties and had a complex medical history including heart defects, deafness, epilepsy, schizophrenia, and cataracts.
- MRI revealed brain ventriculomegaly and spinal stenosis from ossification of the yellow ligament, leading to a diagnosis of 22q11.2 deletion syndrome (22q11.2DS).
- The case highlights the importance of considering 22q11.2DS in adults, as it was previously undiagnosed, and suggests that the spinal condition may be linked to hypoparathyroidism.
Age-related changes in blood pressure and heart rates of patients with Parkinson's disease.
J Clin Hypertens (Greenwich)
January 2021
This study evaluated yearly changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rates (HR) for patients with Parkinson's disease (PD). Data were collected for the last 10 years from medical records of 28 PD patients and 30 non-PD patients with other neurological disorders. Age-related changes in each group were analyzed by year using mean values of SBP, DBP, and HR obtained at their bi-monthly visits.
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- The study aimed to evaluate cutaneous vasomotor neural function in patients with multiple system atrophy (MSA) to assess the severity of central autonomic dysfunction.
- Researchers measured several parameters, including skin sympathetic nerve activity (SSNA) and skin blood flow responses, in 24 MSA patients at rest and after stimulation.
- Findings indicated correlations between resting SSNA reflex latency and disease duration, suggesting that poorer thermoregulatory function may be present even in patients with shorter disease duration, highlighting the potential of measuring sympathetic activity as a predictive tool for autonomic dysfunction in MSA.