Synopsis of recent research by authors named "Akane Okada"
- Akane Okada’s recent research focuses on innovative genetic engineering techniques utilizing artificial chromosomes, particularly in the context of enhancing gene delivery and developing transchromosomic mice for therapeutic antibody production.
- The studies highlight the use of mouse artificial chromosomes to improve homology-directed repair efficiency in mammalian cells, as well as exploring the potential of these vectors for engineering human induced pluripotent stem cells for therapeutic applications.
- Additionally, research on the effects of dimethyl fumarate on triple-negative breast cancer cells demonstrates its potential as a therapeutic agent by inhibiting NF-κB, thus promoting apoptosis and improving the efficacy of conventional cancer treatments.
