Chronic Kidney Disease and Its Clinical Correlates in a Rural Community in Southwestern Nigeria.

Chronic kidney disease (CKD) is a burgeoning problem globally, and more than a billion adults were affected as of 2016, with 1.2 million people dying from renal failure in 2017. To arrest the seemingly relentless progression of CKD to renal failure, there is a need to detect CKD early in the community.

Bioactivity properties of hydroxyapatite/clay nanocomposites.

The need for bioactive and non-toxic biomaterials is on a high demand in tissue engineering applications nowadays. Hydroxyapatite (HAp) is the chief constituent of teeth and bones in mammas. One of the major challenges with the use of HAp in engineering application is its brittleness and to overcome this, it's important to react it with a material that can enhanced it's fragility.

Empirical analysis of South African's urbanization growth and export demands: implications for environmental sustainability.

South African economy is widely known to contribute significantly to the carbon emissions due to usage of heavy machinery and equipment involved in production process. This study examines the linkage among carbon emissions, export, gross domestic product, and urban population growth in South Africa. The study employs the Autoregressive Distributed Lag model to evaluate the linkage among outlined variables, using annual data from 1981 to 2021.

Socio-economic drivers and effects of contraceptive usage on breast cancer among women in Nigeria.

Certain types of contraceptives might have adverse effects on women's health including the possibility of causing breast cancer (BC). Furthermore, the types of contraceptives used might depend on the socioeconomic status of women. The triangular linkage of socioeconomic factors, contraceptives, and some factors causing BC among women are scarce in the literature, especially in developing countries.

Analysis of Household Daily Water Consumption Dynamics in the Tropical Environment.

Understanding daily water use determinants is critical to sustainable water access and its efficient use at household level. To pursue this objective, primary data were generated through a survey of 276 respondents across the 5 quarters into which the city of Iwo is divided. 67.

Sustainable electricity consumption in South Africa: the impacts of tourism and economic growth.

The current study examines sustainable electricity consumption for economic growth in a small open and tourist economy. The energy-tourism nexus is evaluated for the relationship between sustainable electricity consumption and the international tourist arrival for the South African economy. The present study leverages on annual frequency data for South Africa from 1995 to 2019 for empirical analysis using the ARDL technique.

Potency of some economic variables affecting environmental quality in Nigeria.

Environmental quality (EQ) is germane to achieving sustainable living on earth. To evaluate a related stimulus of EQ on area basis, a comparative analyses of economic factors that influence pollution in Iwo and Ibadan metropolis was carried out. Data for the study was generated through the administration of 700 structured questionnaires in total at both locations, out of which 165 and 473 were retrieved from Iwo and Ibadan respectively.

Financial literacy and inclusion for rural agrarian change and sustainable livelihood in the Eastern Cape, South Africa.

Finance and growth underpin the debate on the implication of financial literacy and financial inclusion for development among scholars. While financial inclusion and financial literacy are positioned as enablers of sustainable development, literature has failed to link the two with sustainable development, especially for rural agrarian dwellers in dire need of financial development attributes. Therefore, this study applied variance-based structural equation modelling to examine the implication of financial literacy and financial inclusion for the sustainable livelihood of rural agrarian settlers in the Eastern Cape province of South Africa.

Prevalence of hepatitis B virus infection among children attending the outpatient clinic of a tertiary health centre in Southwest Nigeria.

Introduction: hepatitis B virus (HBV) infection is a global health disease. One-third of the world´s population is reportedly infected with the virus. Infections in children are mostly perinatal and therefore acquired early in life, with a propensity to evolve into chronic diseases and their attendant life-threatening complications.

Psychoactive substance abuse among commercial bus drivers in Umuahia, Abia State, South-Eastern Nigeria: an uncontrolled "epidemic" with attendant road traffic crashes.

Background Information: The unprecedented depletion of the productive workforce has been majorly attributed to road traffic crashes (RTCs). The attendant consequences of this depletion have been found to constitute a serious global public health challenge, with the use of psychoactive substances among drivers implicated in every three of five motor vehicle accidents. Hence, this study assessed the pattern and explored the determinants of substance abuse among commercial bus drivers in Umuahia, Abia State.

Economic factors affecting environmental pollution in two Nigerian cities: A comparative study.

Environmental quality is a sustainability issue influenced by economic realities. To understand their relationships and influence, a comparative study of economic factors that affect pollution in Iwo and Ibadan metropolia was carried out. Data for the study was generated by administering 1067 structured questionnaires at both locations out of which 215 and 658 were, respectively, retrieved from Iwo and Ibadan.

The Prevalence and Pattern of Anaemia in Type 2 Diabetics in Ogbomosho, An Urban Community in Southwestern Nigeria.

Anaemia is a frequent finding in type 2 diabetes, but it is typically seen with established chronic kidney disease and renal insufficiency. Cases, where anaemia predates renal insufficiency, are associated with a worse prognosis for the type 2 diabetes patient and an increased susceptibility to complications. This study aims to determine the prevalence and type of anaemia in persons living with type 2 diabetes without established chronic kidney disease in our environment.

Health insurance in private and public health facilities in Southwestern Nigeria: what determines clients´ satisfaction with quality of service?

Introduction: insured-persons have complained about poor quality of services rendered by health care providers, which has consequently affected their satisfaction with care received. The objectives of this study aimed to identify the determinants of satisfaction and compare the level of clients´ satisfaction with quality of care received in both public and private health care facilities, in Oyo-State, Nigeria.

Methods: this was a cross sectional study, comparative in design.

Hypertension and its Clinical Correlates in a Rural Community in South Western Nigeria.

Background: Hypertension is the commonest cardiovascular risk factor globally and is a cause of untold morbidity and mortality. However, its clinical correlates at the community level have not been well elucidated.

Methods: History taking, anthropometric measurements, electrocardiograms and laboratory investigations were done for all the study subjects.

Evaluation of access to different legume pastures on performance and welfare of broiler chickens during dry season under tropical environment.

There have been a plethora of studies on the effects of access to runs on chickens' welfare and behavioural repertoire with a paucity of information on the comparative advantage of various legume pasture and deep litter system. A total of 200-day-old unsexed Marshall Broiler chicks were weighed and assigned randomly into five experimental groups, viz. deep litter without access to run (DL), deep litter with access to Stylosanthes hamata (SH), Stylosanthes guanensis (SG), Mucuna pruriens (MP) and free run (FR) during dry season.

Rifampicin-Resistant Tuberculosis in a Toddler: A Report of a Rare Paediatric Case in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.

The emergence of resistant strains of mycobacterium tuberculosis (TB) to antituberculous drugs has compounded the management of the chronic infection. More than 90% of rifampicin (RIF)-resistant isolates are also isoniazid resistant; hence, rifampicin resistance (RR) is a surrogate marker for multidrug resistant TB (MDR-TB). Although there are limited reports of pediatric RR/MDR-TB in Nigeria, there had not been similar report in our hospital until now.

Risk of Obstructive Sleep Apnoea among Adults in a Rural Community in Southwest Nigeria.

Background: Obstructive sleep apnoea (OSA) is a common medical condition which has long been recognized as a major contributor to morbidity and mortality in developed countries but that remains underdiagnosed, particularly in rural communities. This study aimed to assess the prevalence of adults who have a high risk of obstructive sleep apnoea in a sample of adults living in Ejigbo, a rural community in south western Nigeria.

Methods: This was a community-based cross-sectional descriptive study done to assess the prevalence of high risk of obstructive sleep apnoea in adult residents of the community using the STOP-BANG questionnaire.

Plasma Lipids and CD4 Count of Newly Diagnosed HIV Sero-Positive Patients at Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria.

Introduction: The pathogenesis of HIV has been linked to the affectation of a number of CD4 positive T cells upon which the severity of the disease is graded. Patients who present with complications such as disorders of lipid metabolism may be missed if appropriate laboratory investigations are not done. Dyslipidemia is a common phenomenon in patients with HIV infection.

10-year risk for cardiovascular diseases using WHO prediction chart: findings from the civil servants in South-western Nigeria.

Background: Globally, cardiovascular diseases (CVDs) have continued to ravage the human existence through the premature deaths of its workforce. Despite this burden, many studies in Nigeria have focused on determining the prevalence of risk factors which alone are insufficient to assess the risk of future cardiovascular events. Therefore, we determined the pattern and predictors of 10-year risk for CVDs in South-western Nigeria.

Age-specific nomograms for follicle stimulating hormone and anti-Mullerian hormone: A pilot study in Ile-Ife, Nigeria.

Background: Assessment of ovarian reserve is one of the steps in the management of infertile couples. Follicle Stimulating hormone (FSH) and anti-Müllerian hormone (AMH) are commonly used ovarian reserve markers in Africa. However, there is paucity of age-specific reference values for FSH and AMH among the African population.

Formulation and characterization of atropine sulfate in albumin-chitosan microparticles for in vivo ocular drug delivery.

The overall study goal was to produce a microparticle formulation containing atropine sulfate for ocular administration with improved efficacy and lower side effects, compared with that of the standard marketed atropine solution. The objective was to prepare an atropine sulfate-loaded bovine serum albumin-chitosan microparticle that would have longer contact time on the eyes as well as better mydriatic and cycloplegic effect using a rabbit model. The microparticle formulation was prepared by method of spray-drying technique.

In vitro and ex vivo characterization of lectin-labeled Mycobacterium tuberculosis antigen-containing microspheres for enhanced oral delivery.

Purpose: Oral immunization for mucosal protection against Mycobacterium tuberculosis would be the best option for effective tuberculosis (TB) control. However, this route of vaccine delivery is limited due to the short residence time of the delivery system at the site of absorption. Cytoadhension has made it possible to optimize the targeted delivery of oral vaccine to lymphoid tissues.

Targeted delivery of antigens to the gut-associated lymphoid tissues: 2. Ex vivo evaluation of lectin-labelled albumin microspheres for targeted delivery of antigens to the M-cells of the Peyer's patches.

The purpose of this study was to evaluate the possibility of lectin-coupled microspheres to improve the targeted delivery of protein antigens to the lymphoid tissues of mucosal surfaces. Bovine serum albumin containing acid phosphatase model protein and polystyrene microspheres were coupled with mouse M-cell-specific Ulex europaeus lectin. The coupling efficiency, physical characteristics and the binding capabilities of the microspheres to the follicle associated epithelium of the Peyer's patches were evaluated in vitro and ex vivo in mice intestine.