Inclusion complexes between amphiphilic phenyleneethynylene fluorophores and cyclodextrins in aqueous media.

Binding events of cyclodextrins (CyD's) in aqueous media are important for designing and explaining the host-guest chemistry applied in sensing and controlled release systems. A water-soluble tricationic compound (3N(+)) with three branches of phenyleneethynylene fluorescent moieties and its related amphiphilic compounds (3C(-), N(0)N(+), N(+), and 2N(+)) are employed as molecular probes in the systematic characterization of the supramolecular interactions with CyD's (α, β, and γ). The strong fluorescence enhancement, combined with induced circular dichroism (CD) signals and (1)H NMR data, is evidence of 1:1 static inclusion complexes of 3N(+)/γ-CyD and 2N(+)/γ-CyD.