Publications by authors named "Ajuan Shen"
Article Synopsis
- Lung adenocarcinoma (LUAD) is linked to high mortality rates, and the protein S100A16 is suggested to have prognostic importance in this cancer, although its exact mechanism is unclear.
- The study analyzed S100A16 expression in LUAD tissues and cells, revealing that higher levels of S100A16 correlate with poorer patient outcomes and that reducing S100A16 decreases cell growth, migration, invasion, and angiogenesis.
- It was found that S100A16 interacts with the MOV10 protein, stabilizes ITGA3 mRNA, and affects ECM-receptor interactions, ultimately enhancing the aggressive characteristics of LUAD.
