Publications by authors named "Ajitesh Ojha"
Article Synopsis
- - The case discusses a 64-year-old woman with a complex set of symptoms including difficulty speaking and swallowing, which led to the consideration of various potential diagnoses, including neurosarcoidosis.
- - Diagnostic procedures revealed cranial nerve palsies; while MRI was inconclusive, CT scans indicated vocal cord paralysis, and lab tests showed elevated CSF biomarker levels, supporting the diagnosis of neurosarcoidosis.
- - Treatment with steroids and infliximab showed significant improvement in her symptoms and highlights the importance of CSF sIL-2R as a useful biomarker while also promoting the use of steroid-sparing therapies in managing the condition.
Introduction: Polymerase chain reaction (PCR) testing of cerebrospinal fluid (CSF) is a sensitive and specific method in diagnosing herpes simplex virus (HSV) encephalitis. However there are increasing reports of false negative HSV PCR.
Case Description: We present a patient in the 9 decade of life with abnormal behavior and focal seizures with MRI showing a right temporal T2 hyperintense non-enhancing lesion with electrographic evidence of right lateralized periodic discharges.
Progressive multifocal leukoencephalopathy (PML) is a life-threatening central nervous system (CNS) disorder, most commonly described in patients infected with the human immunodeficiency virus (HIV). Limited data exist on its natural history and treatment in solid organ transplant (SOT) recipients. A complication of PML is the immune reconstitution inflammatory syndrome (IRIS), which develops after T cell reconstitution and can have severe consequences when it occurs in the CNS.
View Article and Find Full Text PDFIntroduction: Since the late 1980s, critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) have been increasingly recognized in the intensive care unit (ICU). We explored whether these causes of ICU weakness were now more likely to lead to electrodiagnostic studies (EDX) at our institution than they were 19-20 years earlier.
Methods: We reviewed 100 consecutive ICU patients who underwent EDX from 2009 to 2015 and compared them to a previously reported study population from 1990-1995.
Objective: To investigate the frequency of various nonorthostatic complaints in children with postural orthostatic tachycardia syndrome (POTS).
Study Design: We used our autonomic laboratory database to identify all pediatric patients with traditionally defined POTS who had completed the Ohio Dysautonomia Survey (ODYSA). The responses of the patients to questions targeting various autonomic complaints, including syncope, gastrointestinal symptoms, sleep disturbances, headaches, urinary symptoms, chronic pain, and Raynaud-like symptoms, were collected and analyzed.
Background: There are conflicting opinions on whether postural tachycardia syndrome predisposes to syncope. We investigated this relationship by comparing the frequency of syncope in postural tachycardia syndrome and orthostatic hypotension.
Methods: We queried our autonomic laboratory database of 3700 patients.