Publications by authors named "Ajit Rao"

Inferior pancreaticoduodenal artery aneurysm (IPDA) with the stenosis of the celiac axis is rare and may cause rupture. A unique etiology of IPDAs with celiac stenosis is median arcuate ligament syndrome. These aneurysms develop as a result of the dilation of the arteries from the retrograde blood flow into the pancreaticoduodenal arches because of celiac artery compression by the median arcuate ligament.

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Progressive peripheral artery disease, especially in the tibial and pedal vessels, can severely limit the interventions that vascular surgeons and interventionalists can provide to patients. End-stage peripheral arterial disease is often described as a disease where there are no distal targets available in the foot. Traditionally, amputation has been the only option for these patients.

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Background: Traditionally, extracranial carotid artery aneurysms or pseudoaneurysms (ECCAs) have been managed through open surgical repair. Recent literature highlights the increasing success of endovascular techniques in treating ECCAs. Our study explores our center's experience with endovascular management of ECCAs, including the innovative use of transcarotid artery revascularization (TCAR) at a tertiary-care center.

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Article Synopsis
  • * Symptoms usually arise from the aneurysm pressing on nearby structures, but serious issues like rupture or blood clots can also occur.
  • * A case study of a 30-year-old woman shows successful treatment of a 15-mm asymptomatic right-sided SAA using surgical resection and end-to-end anastomosis.
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  • The study compares the outcomes of transcarotid artery revascularization (TCAR) and transfemoral carotid artery stenting (tfCAS) over a 3-year period, finding TCAR has significantly lower mortality rates, especially in the first 6 months.
  • It analyzed data from over 70,000 patients and adjusted for various demographic and clinical factors, revealing that TCAR patients had higher comorbidities and were older.
  • The results indicate that TCAR is associated with a 24% reduction in mortality hazard compared to tfCAS, suggesting it may be the better option for patients needing carotid artery interventions.
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Peripheral artery disease (PAD) can present as chronic limb threatening ischemia (CLTI) with ischemic pain and tissue loss. Progression of distal disease can lead to a "no option" or end-stage disease without traditional open or endovascular revascularization due to lack of pedal targets. Innovations in endovascular technology allow for the use of percutaneous deep vein arterialization (pDVA) to treat patients with CLTI.

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  • The study aimed to analyze TEVAR outcomes among different weight classes (normal, overweight, and obese) to identify complications, reintervention rates, and short-term mortality.
  • A total of 204 patients were analyzed, revealing that obese patients were generally younger and had higher rates of type B aortic dissection, compared to normal-weight patients who mostly had thoracic aortic aneurysms.
  • Despite the differences in patient characteristics, the study found no significant differences in intraoperative or postoperative complications, reintervention rates, or survival outcomes across the weight categories.
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Background: The purpose of this study was to assess outcomes after spinal anesthesia (SA) versus general anesthesia (GA) in patients undergoing thoracic endograft placement and to evaluate the adjunctive use of cerebrospinal fluid drainage (CSFD) placement.

Methods: A single-center retrospective review of patients that underwent thoracic endograft placement from 2001 to 2019 was performed. Patients were stratified based on the type of anesthesia they received: GA, SA or epidural, GA with CSFD, and SA with CSFD.

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  • This study investigates the risks and outcomes of carotid artery stenting (CAS) in patients with a history of neck radiation, focusing on two methods: transfemoral carotid artery stenting (TFCAS) and transcarotid artery revascularization (TCAR) over 30 days and 3 years.* -
  • Data from 72,656 patients revealed no significant difference in major perioperative complications (like stroke or death) between those with and without prior neck radiation, suggesting similar safety profiles for both procedures.* -
  • However, TCAR showed a lower risk of access site complications and a lower chance of combined adverse outcomes (stroke, death, myocardial infarction) for patients with prior neck radiation, although
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  • Acute deep venous thrombosis (DVT) is a major public health issue in the U.S., affecting over 350,000 individuals each year and leading to significant economic costs and health complications like post-thrombotic syndrome (PTS).
  • Treatment strategies for acute DVT have evolved since 2008, with national guidelines now recommending various interventional approaches in addition to traditional anticoagulation and conservative management.
  • New endovascular techniques and technologies have been developed that reduce risks associated with older treatments, allowing healthcare providers to customize treatment plans based on individual patient needs.
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  • The study investigated outcomes of iliac vein stenting in patients with chronic proximal venous outflow obstruction, comparing those with and without superficial venous insufficiency (SVI).
  • A total of 553 patients were analyzed, with two groups: one without SVI (178 patients) and another with SVI (375 patients), showing significant differences in age, body mass index, diabetes, hypertension, and coronary artery disease.
  • Results indicated that while both groups had similar improvements in symptoms, patients with SVI were significantly more likely to require additional minor postoperative procedures.
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Introduction: Asymptomatic patients with a remote history of transient ischemic attack (TIA) or stroke are not well studied as a separate population from asymptomatic patients with no prior history of TIA or stroke. We compared in-hospital outcomes after transcarotid artery revascularization (TCAR) and transfemoral carotid artery stenting (TFCAS) among symptomatic patients, patients with a remote history of neurologic symptoms, and asymptomatic patients.

Methods: Data from patients in the Vascular Quality Initiative database who underwent TCAR (January 2017 to April 2020) or TFCAS (May 2005 to April 2020) were analyzed.

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Infection with severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2/Covid-19) has been correlated with micro and macrovascular thrombosis. Reports have discussed localized thrombosis leading to ischemia, we report a case of diffuse systemic thromboembolism resulting in limb ischemia and organ damage from Covid-19 despite prompt anticoagulation. A 60-year-old unvaccinated male with a history of asthma, diabetes mellitus and coronary artery disease, presented with shortness of breath and right lower extremity pain.

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Peripheral artery disease (PAD) can often present with chronic limb threatening ischemia (CLTI), including ischemic rest pain and severe tissue loss. Progression of PAD can lead to "no option" or end-stage disease in which there are no traditional open or endovascular interventions available for revascularization. This cohort of patients have a poor prognosis, with a major amputation rate of 40% and mortality of up to 20% at six months.

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Background: Anatomic details affecting the adverse outcomes following carotid artery stenting have not been well characterized. We compared in-hospital outcomes following transcarotid artery revascularization (TCAR) and transfemoral carotid artery stenting (TFCAS) among symptomatic and asymptomatic patients stratified by degree of lesion calcification and aortic arch type.

Methods: Data from patients in the Society for Vascular Surgery's Vascular Quality Initiative database undergoing TCAR (January 2017 to April 2020) or TFCAS (May 2005 to April 2020) and had non-missing grading on carotid artery calcification or aortic arch type was analyzed.

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We describe a case of nutcracker syndrome in a 35 year-old male that was treated with a left renal vein transposition via an open retroperitoneal approach. Our case highlights some of the advantages of the retroperitoneal approach, which may decrease the risk of postoperative complications when compared to the traditional midline abdominal transperitoneal approach. The patient agreed to publish the case details and images included below.

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Objective: COVID-19 infection results in a hypercoagulable state predisposing patients to thrombotic events. We report the 3- and 6-month follow-up of 27 patients who experienced acute arterial thrombotic events in the setting of COVID-19 infection.

Methods: Data were prospectively collected and maintained for all vascular surgery consultations in the Mount Sinai Health System from patients who presented between March 16 and May 5, 2020.

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Background: The blood neutrophil-to-lymphocyte ratio (NLR) is a surrogate biomarker of systemic inflammation with important prognostic significance in multiple disease processes, including cardiovascular diseases. It is inexpensive, widely available, and may be related to the outcomes of patients after surgery. We aimed to investigate the possible association of NLR with the outcomes of patients following endovascular aneurysm repair (EVAR).

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New York City was one of the epicenters of the COVID-19 pandemic. The management of peripheral artery disease (PAD) during this time has been a major challenge for health care systems and medical personnel. This document is based on the experiences of experts from various medical fields involved in the treatment of patients with PAD practicing in hospitals across New York City during the outbreak.

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Introduction: With the aging U.S. population, peripheral vascular procedures will become increasingly common.

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Background: Both arterial and venous thrombotic events of the extremities occur in coronavirus disease 2019 (COVID-19) infection, but the etiology of these events remains unclear. This study sought to evaluate pathology specimens of COVID-19-positive patients postamputation, who were found to have Rutherford 3 acute limb ischemia requiring amputation.

Methods: A retrospective review was performed of all vascular surgery emergency room and inpatient consultations in patients who presented to the Mount Sinai Health System from March 26, 2020, to May 10, 2020.

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Efficacy of duplex ultrasound (DU) surveillance of complex EVAR such as FEVAR and ChEVAR has not been studied. All patients undergoing FEVAR or ChEVAR at a single multihospital institution were retrospectively reviewed. Postoperative surveillance included DU at 1 month and CTA at 3 months.

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Background: Coronavirus disease 2019 (COVID-19) is a novel coronavirus that has typically resulted in upper respiratory symptoms. However, we have encountered acute arterial and venous thrombotic events after COVID-19 infection. Managing acute thrombotic events from the novel virus has presented unprecedented challenges during the COVID-19 pandemic.

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We describe three patients with COVID-19 who presented with an acute vascular event rather than with typical respiratory symptoms. These patients were all subsequently found to have laboratory-confirmed COVID-19 infections as the likely cause of their thrombotic event. The primary presentation of COVID-19 infection as a thrombotic event rather than with respiratory symptoms has not been described elsewhere.

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