Venous thromboembolism in patients with surgically treated ankle fractures.

Objectives: In patients with rotational ankle fracture, we compare the rate of venous thromboembolism development between patients who received chemoprophylaxis vs those patients that received none.

Design: Retrospective cohort study.

Setting: Level I trauma center.

Techniques for predicting and avoiding unintentional biplanar movements during iliosacral screw placement.

The technique for placing iliosacral screws typically involves the surgeon using an inlet and outlet view as the primary means for assessing the anteroposterior and craniocaudal position of the guidewire, respectively. However, because these views are rarely, if ever, orthogonal to one another, this technique will inevitably lead to unintentional biplanar movements. These unintentional movements, in turn, require correction, which can increase operating room and fluoroscopic time.

The Natural History of Pediatric Trigger Thumb in the United States.

Purpose: Surgical release of pediatric trigger thumbs has been recommended as definitive treatment, although controversy exists over the natural history of pediatric trigger thumb. This study sought to evaluate the incidence of spontaneous resolution of pediatric trigger thumb and the factors that may influence resolution.

Methods: Pediatric patients were prospectively enrolled by a single surgeon from August 2009 to July 2015.

Closed manipulation under anesthesia for pediatric post-traumatic elbow arthrofibrosis.

Background: Post-traumatic elbow arthrofibrosis (PEA) and its associated limitations to elbow range of motion (ROM) are a recognized consequence of trauma to the pediatric elbow. Closed manipulation under anesthesia (CMUA) of the elbow can be performed in pediatric patients as a nonoperative attempt to improve dysfunctional ROM. Minimal outcome data to support CMUA exist.

Compartment Syndrome in Tibial Plateau Fractures: Do Previously Established Predictors Have External Validity?

Objective: To test previously established radiographic predictors of compartment syndrome in tibial plateau fractures and determine whether novel measurements may further improve a surgeon's ability to identity patients at high risk for developing this outcome.

Design: Retrospective review.

Setting: Academic Level I trauma center.

Unstable Pelvic Ring Injuries: How Soon Can Patients Safely Bear Weight?

Objective: To determine if time to weight bearing (WB) is associated with complications in operatively treated pelvic ring injuries.

Design: Retrospective cohort study.

Setting: Academic Level I trauma hospital.

Association of Physical Function, Anxiety, and Pain Interference in Nonshoulder Upper Extremity Patients Using the PROMIS Platform.

Purpose: The relationship between psychosocial factors and self-reported physical function among hand and upper extremity patients is complex. The Patient-Reported Outcomes Measurement Information System (PROMIS) platform has attempted to create a variety of specifically targeted metrics that can be administered using computer adaptive testing (CAT). Three metrics measuring self-reported physical function (herein referred to in combination as "functional" metrics) include the PROMIS Physical Function (PF) CAT, PROMIS Upper Extremity (UE) CAT, and the Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH).

Treatment Approach for Infection of Healed Fractures After Internal Fixation.

Objective: To review the efficacy of a treatment approach for patients with infection and colonized implants after open reduction and internal fixation of fractures.

Design: Retrospective case series.

Setting: Level one trauma center.

Serial Radiographs Do Not Change the Clinical Course of Nonoperative Stable OTA/AO 44-B1 Ankle Fractures.

Objective: To assess radiographic markers of ankle stability in stable OTA/AO 44-B1 ankle fractures.

Design: Retrospective review.

Setting: Academic Level-I trauma hospital.

Provoked exercise desaturation in patent foramen ovale and impact of percutaneous closure.

Objectives: This study was designed to assess the prevalence of provoked exercise desaturation (PED) in patients with patent foramen ovale (PFO) referred for cardiovascular evaluation and to evaluate the impact of PFO closure.

Background: Platypnea orthodeoxia syndrome is a rare, mechanistically obscure consequence of PFO that results in oxygen desaturation during postural changes. In our clinical experience, however, it is far less common than desaturation during exercise.

An ex-ovo chicken embryo culture system suitable for imaging and microsurgery applications.

Understanding the relationships between genetic and microenvironmental factors that drive normal and malformed embryonic development is fundamental for discovering new therapeutic strategies. Advancements in imaging technology have enabled quantitative investigation of the organization and maturing of the body plan, but later stage embryonic morphogenesis is less clear. Chicken embryos are an attractive vertebrate animal model system for this application because of its ease of culture and surgical manipulation.

Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects.

Embryonic heart formation is driven by complex feedback between genetic and hemodynamic stimuli. Clinical congenital heart defects (CHD), however, often manifest as localized microtissue malformations with no underlying genetic mutation, suggesting that altered hemodynamics during embryonic development may play a role. An investigation of this relationship has been impaired by a lack of experimental tools that can create locally targeted cardiac perturbations.