Have Degree, Will Travel? Geography and Orthopaedic Surgery Residency Match.

Introduction: The paucity of objective data on the residency application is challenging to Orthopedic Surgery residency programs when selecting candidates to interview and to rank. Qualifying or quantifying the effect of geography on match results will help programs screen and rank candidates more effectively. The aim of this study is to describe the geographic background of current Orthopedic Surgery residents in the United States relative to their current residency program.

Genetic Silencing of Fatty Acid Desaturases Modulates α-Synuclein Toxicity and Neuronal Loss in Parkinson-Like Models of .

The molecular basis of Parkinson's disease (PD) is currently unknown. There is increasing evidence that fat metabolism is at the crossroad of key molecular pathways associated with the pathophysiology of PD. Fatty acid desaturases catalyze synthesis of saturated fatty acids from monounsaturated fatty acids thereby mediating several cellular mechanisms that are associated with diseases including cancer and metabolic disorders.