Pattern of Right Ventricular Changes in Patients with Uncomplicated Systemic Hypertension at a Tertiary Centre in Southwest Nigeria.

Background And Aims: Hypertension is an independent risk factor for cardiovascular complications. The effect of systemic hypertension on the right ventricle (RV) has received less attention probably due to its complex structure and location. The aim of the study was to assess the effect of systemic hypertension on the structure and function of the right ventricle using transthoracic echocardiography.

Impact of Anemia on The Quality of Life of Chronic Kidney Disease Patients: A Single Institution Experience.

Background: Anemia is a common complication of chronic kidney disease (CKD) and has been shown to worsen as CKD advances. CKD negatively impacts patients' health-related quality of life. It is therefore necessary to determine the impact of anemia on the quality of life in patients with CKD.

Plasma paraoxonase-1 activity levels in patients with type 2 diabetes mellitus in Lagos State University Teaching Hospital, Lagos, Southwest Nigeria: a cross-sectional study.

Introduction: paraoxonase 1 (PON1) is a high-density lipoprotein (HDL) associated enzyme that has anti-inflammatory, anti-atherogenic, and antioxidant functions. PON1 is noted to be a determinant of resistance to the development of atherosclerosis through hydrolysis of phospholipid and cholesteryl ester hydroperoxides. This study was designed to assess PON1 activity levels among patients with type 2 diabetes mellitus (T2DM) in Southwest Nigeria.

Evaluation of water pollution monitoring for heavy metal contamination: A case study of Agodi Reservoir, Oyo State, Nigeria.

Heavy metals affect the suitability of aquatic environment for all purposes; hence, this study evaluated heavy metal contamination in Agodi Reservoir Oyo State, Nigeria. Atomic Absorption Spectrophotometry was used to determine heavy metal concentrations. Heavy Metal Pollution Index (HPI), Water Quality Index (WQI), Pollution Index (PI), Comprehensive Pollution Index (CPI), Contamination Index (CI), Single-Factor Pollution Index (SFPI), Heavy metal Evaluation Index (HEI), and Human Health Risk Assessments (HRA) were used to determine the extent of heavy metal pollution and their impact on the aquatic environment.

Bio-tolerance potential and environmental risks assessment of Oreochromis niloticus and Ipomoea aquatica in Agodi Reservoir, Nigeria.

The concentration of nine heavy metals in Oreochromis niloticus and Ipomoea aquatica inhabiting Agodi reservoir, Oyo State, Nigeria were investigated for twelve months. The concentrations of the metals were carried out using PG990 Atomic Absorption Spectrophotometer. The Ecological Risk Quotient (ERQ) was calculated using standard methods while the tolerability was determined with Box Plot analysis.

Textural characteristics and geochemical composition of a tropical coastal marine sediment: a case study of transgressive mud beach, Bight of Benin, Nigeria.

The study determines the textural characteristics and geochemical composition of the transgressive mud coastal marine sediments of the Bight of Benin, Nigeria. The sediment samples were collected using a VanVeen grab sampler from three onshore and three offshore locations. The particle size analysis was conducted with a combination of the pipette sampling and wet sieving of the fraction > 62-µm method, while the concentrations of major oxides were determined by employing X-ray fluorescence technique.

Assessment of Ventricular Repolarization in Sickle Cell Anemia Patients: The Role of QTc Interval, Tp-e Interval and Tp-e/QTc Ratio and Its Gender Implication.

Background: Many specific and non-specific electrocardiographic abnormalities including ventricular arrhythmias have been reported in subjects with sickle cell anemia (SCA). In SCA patients, cardiac electrical abnormalities may be the leading cause of increased risk of arrhythmias. The corrected QT (QTc) interval, peak to the end of the T wave (Tp-e) interval and associated Tp-e/QTc ratio are promising measures of altered ventricular repolarization and increased arrhythmogenesis risk.

Heart rate variability and arrhythmic patterns of 24-hour Holter electrocardiography among Nigerians with cardiovascular diseases.

Background: Facilities for Holter electrocardiography (ECG) monitoring in many Nigerian hospitals are limited. There are few published works in Nigeria on the use of 24-hour Holter ECG in cardiac arrhythmic evaluation of patients with cardiovascular diseases.

Objective: To study the clinical indications, arrhythmic pattern, and heart rate variability (HRV) among subjects referred for 24-hour Holter ECG at our Cardiac Care Unit.

Pattern of arrhythmias among Nigerians with congestive heart failure.

Background: In patients with heart failure, death is often sudden due to life-threatening arrhythmias. This work was carried out to evaluate the pattern of arrhythmias in Nigerians with heart failure.

Materials And Methods: Thirty subjects with congestive heart failure (CHF), 30 subjects with hypertensive heart disease, and 15 normal subjects with no obvious features of heart disease were evaluated with resting and 24-hour electrocardiographic monitoring and transthoracic echocardiography.

The effect of psychological distress on medication adherence in persons with HIV infection in Nigeria.

Background: A high level of adherence to prescribed antiretroviral (ARV) regimens is required to achieve and maintain suppression of human immunodeficiency virus (HIV) replication and prevent drug resistance.

Objective: This study aimed to determine the possible relationship between psychopathology and ARV medication adherence in Nigeria.

Method: Persons with HIV infection (N=182) completed various questionnaires on sociodemographic and clinical details, general psychopathology, self-esteem, and medication adherence.

Post-traumatic stress disorder (PTSD) after stigma related events in HIV infected individuals in Nigeria.

Background: One of the most distressing concerns of many people living with HIV in sub-Saharan Africa is the stigma. Intense stigma may be traumatic. This study aimed to investigate the probability and correlates of Posttraumatic stress disorder (PTSD) following intense stigmatizing events and situations in HIV infected individuals in Nigeria.

Relationship between depression and quality of life in persons with HIV infection in Nigeria.

Objective: Despite the fact that two-thirds of all the people with HIV live in sub-Saharan Africa, little is known about the emotional state and quality of life (QOL) of subjects with HIV in this region. The objective of this study was to evaluate the association between clinical depression and quality of life in a group of HIV sero-positive subjects in Nigeria.

Methods: Subjects with HIV infection (n = 87) completed a questionnaire detailing sociodemographic and HIV related variables.

Psychiatric disorders among the HIV-positive population in Nigeria: a control study.

Objective: This article estimates the point prevalence of psychiatric disorders in a sample of HIV-positive subjects in Nigeria in comparison with normal HIV-negative controls and evaluates the possible sociodemographic and clinical correlates of psychiatric disorders in HIV-positive subjects.

Methods: HIV-positive subjects (n=88) and HIV-negative healthy controls (n=87) were assessed for their current diagnosis of DSM-IV psychiatric disorders via the Mini International Neuropsychiatric Interview. Sociodemographic and clinical details were also obtained.