Ability of presepsin concentrations to predict mortality in adult patients with sepsis.

Background: Early diagnosis of sepsis is essential for a favorable disease outcome. The aim of this study was to evaluate the association of initial and subsequent presepsin concentrations with sepsis outcomes.

Methods: One hundred sepsis patients were enrolled in the study from two different university centers.

Presepsin values as markers of severity of sepsis.

Objectives: Biomarkers are widely used for rapid diagnosis of sepsis. This study evaluated the diagnostic accuracy of presepsin, procalcitonin (PCT), and C-reactive protein (CRP) in differentiating sepsis severity as well as their association with Sepsis-related Organ Failure Assessment (SOFA) score.

Methods: One hundred septic patients from two university clinical centers were enrolled in the study during two time periods.