Publications by authors named "Ajayi J"

Article Synopsis
  • Resistant hypertension occurs when patients have high blood pressure that doesn't respond to standard medications like beta-blockers and diuretics, leading to serious health risks such as stroke and heart failure.
  • Renal denervation (RDN) is an invasive procedure introduced as an alternative treatment for those with resistant hypertension, showing promise in terms of safety and short-term benefits, but with potential long-term complications like renal stenosis.
  • Further research is needed to explore RDN's effectiveness, develop tailored treatment strategies, and identify biomarkers that can predict outcomes for patients undergoing this procedure.
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Article Synopsis
  • * Semaglutide shows promise in improving symptoms, aiding weight management, and possibly boosting exercise capacity, although its effects on heart function and the exact benefits remain unclear.
  • * While semaglutide has a generally favorable safety profile, further research is needed to confirm its effectiveness, explore optimal dosages, and understand its mechanisms before establishing it as a standard treatment for HFpEF.
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Conversion of dumpsites to farm lands in several communities is a usual practice in Nigeria. Wastes accumulate heavy metals in a variety of forms. This study assessed the concentration, degrees of contamination, and attendant health risk of heavy metals (HMs), using two major indigenous vegetables (Amaranthus viridis and Talinum triangulare) grown on five major dumpsites in Lagos state.

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Spices are essential group of agricultural products used to enrich taste and enhance nutritional contents of foods and beverages. Spices for various types of food were produced naturally from local available plant materials which have been used since the Middle Ages for flavoring, food additives and preservation, supplement, and/or medicinal purposes. Six spices, namely, (yellow pepper), (black pepper), (ginger), (scent leaf), castor seed (ogiri), and (curry leaf), were selected in their natural forms for the production single spices and mixed spices.

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The experiences of family members following Acquired Brain Injury (ABI) are well established, with spouses in particular facing multiple relational and personal changes. Qualitative studies have analysed accounts pertaining to a range of sequelae, however, "change" itself has yet to be addressed. This study explored the experiences of realisation of change for married women living with their husbands following ABI.

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Background: High success rate has been reported widely with conventional endodontic. When failure occurs, re-treatment alone or with surgical endodontics is the recommended treatment.

Objective: To compare the treatment outcome following apicectomy techniques, apicectomy with and without retrograde root - end filling.

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In this study, micro-alloyed steel (MAS) material normally used in the production of auto parts has been immersed in an E80 simulated fuel grade ethanol (SFGE) environment and its degradation mechanism in the presence of sodium chloride (NaCl) was evaluated. Corrosion behavior was determined through mass loss tests and electrochemical measurements with respect to a reference test in the absence of NaCl. Fracture behavior was determined via J-integral tests with three-point bend specimens at an ambient temperature of 27 °C.

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To synergistically enhance the selectivity and efficiency of anticancer copper drugs, we proposed and built a model to develop anticancer copper pro-drugs based on the nature of human serum albumin (HSA) IIA subdomain and cancer cells. Three copper(II) compounds of a 2-hydroxy-1-naphthaldehyde benzoyl hydrazone Schiff-base ligand in the presence pyridine, imidazole, or indazole ligands were synthesized (C1-C3). The structures of three HSA complexes revealed that the Cu compounds bind to the hydrophobic cavity in the HSA IIA subdomain.

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Malaria is a major cause of morbidity and mortality in children and adults in the Sudano Sahel of Northeastern Nigeria with the highest prevalence of malaria in pregnancy of 64.5 in Nigeria recorded in this region. This study was carried out in 2003 and 2004 to provide parasitological baseline data for the development of Malaria Early Warning System (MEWS) for the surveillance of type I epidemic caused by meteorological conditions and to provide data for timing malaria key vector control measures such as Indoor Residual Spraying (IRS) for maximum effect.

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The effect of water contaminated with phenol, benzene and lead on rats cellular system was investigated. Selected enzyme activity of the kidney and colon of rats was carried out. Standard enzyme assays were also conducted for selected liver enzymes such as alkaline and acid phosphatases, alanine and aspartate transaminases, and gamma glutamyl transpeptidase.

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Background: Tooth wear has been generally described as being caused by erosion, abrasion and attrition. Erosion is currently believed to be the major factor involved in tooth wear, and its contribution in the development of tooth wear may be increasing. Among the numerous causes of erosion, extrinsic factors are the most common.

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Hospital based studies were conducted to investigate the occurrence of Plasmodium/intestinal helminth co-infections among pregnant Nigerian women, and their effects on birthweights, anaemia and spleen size. From 2,104 near-term pregnant women examined, 816 (38.8%) were found to be infected with malaria parasites.

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The findings of a prospective study of 656 near-term pregnant; women, and of the cord and peripheral blood of newborns of positive mothers are reported. 292 (44.51%) of the pregnant women were infected with Plasmodium falciparum.

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The effect of malaria parasitaemia on spleen size and anaemia in 1,905 pregnant women in Jos Plateau highlands, Bauchi Savannah plains and Ethiope river basin of Nigeria was evaluated. The overall spleen rates in Jos Plateau, Bauchi and Ethiope were 15, 23, 16.33 and 10.

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Objectives: To establish the prevalence of cord malaria parasitaemia in Nigerians and to elucidate its effect on birthweight.

Design: Case series.

Subjects: 1,905 women resident in three parts of Nigeria.

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Sera from 606 women of child-bearing age from the Benue River Basin area of Nigeria were screened by serological tests to determine the incidence of toxoplasmosis in Nigeria; 43.7% had serologic evidence of infection, increasing from 25% in the group of 15 to 18-year-old women to 71.4% in the 39-42 year age group.

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The findings of a prospective study of 656 near-term pregnant women, and of the cord and peripheral blood of newborns of positive mothers are reported. 292 (44.51%) of the pregnant women were infected with P.

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Leishmania sp. was isolated from the livers and spleens of 4 of 56 Mastomys natalensis and one of 21 Tatera gambiana in Keana District, Nigeria; none of the rodents had cutaneous lesions. Parasites were not found in 42 Rattus rattus.

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Blood samples from 522 children within the ages of 0-9 years attending maternal and child welfare clinics in northern Nigeria who were clinically diagnosed as being malarious were obtained for parasitological examination. Results revealed a parasite rate of 41%, density index of 7.72 and 19.

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The development and survival of the eggs of Haemonchus contortus on pasture at Vom were studied by depositing faecal pellets on grass plots over a period of 12 months. Development and survival to the infective larvae occurred throughout the study except during the dry season months of December to April. More infective larvae were recovered from the herbage in June, July and August than in other months.

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The frequent appearance of patent infestations of Strongyloides papillosus in lambs under one week is observed, and it is suggested that either the short generation interval or pre-natal infection is the cause. Pathogenic effects associated with heavy infestations in young lambs consisted of anorexia, loss of weight, diarrhoea and a moderate anaemia. The lambs were usually very weak, unable to stand and laying prostrate.

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Sporulation rates of normal oocysts and oocysts isolated from lambs infected with coccidia and fed Aureo-S-700R for 25 days were studied at different temperatures. The viability and infectivity of the latter were also investigated. Temperatures of 5 and 10 degrees C inhibited sporulation of oocysts, but when the same oocysts were subsequently incubated at 25 degrees C, they sporulated.

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