Limited significance of bicarbonate therapy in the treatment of diabetic ketoacidosis: a rare case report in the periphery of Nepal.

Introduction And Importance: An uncontrolled hyperglycaemia accompanied by metabolic acidosis and an increase in total body ketone, if left untreated, has the potential to develop into complications, including diabetes ketoacidosis (DKA). Management of this complication with IV hydration, IV Insulin, and potassium (KCL) maintenance is a comprehensive approach. On the contrary, bicarbonate therapy is generally not regarded as a standard treatment due to its unfavourable outcome.

Case Report: Gastric Mucormycosis- a rare but important differential diagnosis of upper gastrointestinal bleeding in an area of Helicobacter pylori endemicity.

A 57 years female from the hills of Nepal presented with upper gastrointestinal bleeding with gastric ulcer evident on endoscopy. Though initially treated with ( ) eradication therapy alone, biopsy later on revealed both mucormycosis and infection. She was then treated with antifungals liposomal amphotericin B followed by posaconazole which led to complete recovery.