Coupling-Induced Dynamic Off-Centering of Cu Drives High Thermoelectric Performance in TlCuS.

Seeking new and efficient thermoelectric materials requires a detailed comprehension of chemical bonding and structure in solids at microscopic levels, which dictates their intriguing physical and chemical properties. Herein, we investigate the influence of local structural distortion on the thermoelectric properties of TlCuS, a layered metal sulfide featuring edge-shared Cu-S tetrahedra within CuS layers. While powder X-ray diffraction suggests average crystallographic symmetry with no distortion in CuS tetrahedra, the synchrotron X-ray pair distribution function experiment exposes concealed local symmetry breaking, with dynamic off-centering distortions of the CuS tetrahedra.

Pilot Study Assessing the Effect of Exam Room Length on the Measurement of Strabismus.

Purpose: Our study aims to investigate the effect of decreasing distance from the patient to the fixation target on the measurement of strabismus with a known distance-near disparity.

Methods: Strabismus measurements were taken by one pediatric ophthalmologist at our standard distance of 18 feet and compared to those taken at 16, 14, 12, and 10 feet from the fixation target. A clinically meaningful difference was defined as >2.

Nanomolecularly-induced Effects at Titania/Organo-Diphosphonate Interfaces for Stable Hybrid Multilayers with Emergent Properties.

Nanoscale hybrid inorganic-organic multilayers are attractive for accessing emergent phenomena and properties through superposition of nanomolecularly-induced interface effects for diverse applications. Here, we demonstrate the effects of interfacial molecular nanolayers (MNLs) of organo-diphosphonates on the growth and stability of titania nanolayers during the synthesis of titania/MNL multilayers by sequential atomic layer deposition and single-cycle molecular layer deposition. Interfacial organo-diphosphonate MNLs result in ∼20-40% slower growth of amorphous titania nanolayers and inhibit anatase nanocrystal formation from them when compared to amorphous titania grown without MNLs.

Chemically Transformed Ag Te Nanowires on Polyvinylidene Fluoride Membrane For Flexible Thermoelectric Applications.

Flexible thermoelectric devices of nanomaterials have shown a great potential for applications in wearable to remotely located electronics with desired shapes and geometries. Continuous powering up the low power flexible electronics is a major challenge. We are reporting a flexible thermoelectric module prepared from silver telluride (Ag Te) nanowires (NWs), which are chemically transformed from uniquely synthesized and scalable tellurium (Te) NWs.

An Analysis of Pediatric Ophthalmology Content on TikTok.

Purpose: To assess pediatric ophthalmology-related information on TikTok (ByteDance).

Methods: The 12 most commonly searched terms from the American Association for Pediatric Ophthalmology and Strabismus website were queried as TikTok hashtags. The top 20 videos for each hashtag were analyzed for views, likes, comments, saves, shares, author status and gender, content, and engagement level ratio (ELR).

2-{N-[(2,4,5-trichlorophenoxy) acetyl]-N-methylamino}-3-pyrrolidinepropanamide analogs as potential antagonists of Urotensin II receptor.

The Purpose Of The Article: To identify novel small molecule antagonists of Urotensin II receptor with acceptable pharmacological profile.

Materials And Methods: Structure-activity-relationship (SAR) studies on 2-{-[(2,4,5-trichlorophenoxy) acetyl]--methylamino}-3-pyrrolidinepropanamide series were conducted and shortlisted compounds were synthesized and evaluated in cell-based assays. Human and mouse Urotensin II receptor overexpressing CHO cells were used for calcium release and radioligand binding assays.

Ocular manifestations in a 2 year-old patient with a DYNC1H1 mutation.

Background: Mutations in the DYNC1H1 gene have been linked to multiple neurologic syndromes with a multitude of clinical manifestations, both ocular and non-ocular. Previous case reports have outlined various ocular phenotypes, including cataracts of congenital onset, infantile onset, and adult onset with lack of further ophthalmologic detail.

Case Presentation: Our case report outlines, in more detail, a 24-month-old male with a heterozygous mutation in the DYNC1H1 gene who developed a white, intumescent cataract in his left eye and a posterior subcapsular cataract in his right eye with evidence of progressive axial myopia.

Autonomic measures identify stress, pain, and instability associated with retinopathy of prematurity ophthalmologic examinations.

Background: Retinopathy of prematurity (ROP) ophthalmologic examinations cause stress and pain. Infants' stress and pain can be measured non-invasively using skin conductance (SC) and high frequency heart rate variability (HF-HRV), reflecting sympathetic-mediated sweating and parasympathetic activity, respectively.

Objectives: To test the utility of SC to detect sympathetic activation during ROP examination, and the contribution of HF-HRV to predict stability post-examination.

Extraocular muscle ductions following nasal transposition of the split lateral rectus muscle.

Objective: To quantify changes in ductions following nasal transposition of the split lateral rectus muscle (NTSLR) for treating third nerve palsy.

Design: Retrospective cohort study.

Participants: A single eye from each patient with third nerve palsy treated with NTSLR with ocular motility measurements.

Glassy thermal conductivity in CsBiICl single crystal.

As the periodic atomic arrangement of a crystal is made to a disorder or glassy-amorphous system by destroying the long-range order, lattice thermal conductivity, κ, decreases, and its fundamental characteristics changes. The realization of ultralow and unusual glass-like κ in a crystalline material is challenging but crucial to many applications like thermoelectrics and thermal barrier coatings. Herein, we demonstrate an ultralow (~0.

Strong Anharmonicity-Induced Low Thermal Conductivity and High n-type Mobility in the Topological Insulator Bi Sb Te S.

Intrinsically low lattice thermal conductivity (κ ) while maintaining the high carrier mobility (μ) is of the utmost importance for thermoelectrics. Topological insulators (TI) can possess high μ due to the metallic surface states. TIs with heavy constituents and layered structure can give rise to high anharmonicity and are expected to show low κ .

Ferrocene anchored activated carbon as a versatile catalyst for the synthesis of 1,5-benzodiazepines one-pot environmentally benign conditions.

1,5-Benzodiazepine is considered as one of the central moieties in the core unit of most drug molecules. Construction of such moieties with a new C-N bond under solvent-free and mild reaction conditions is challenging. Herein, we present a benign protocol for one pot synthesis of 1,5-benzodiazepine derivatives by using ferrocene (FC) supported activated carbon (AC) as a heterogeneous catalyst.

A novel device for digital retinoscopy.

We introduce a portable retinoscopy device designed to allow simultaneous views of the retinoscope's reflex. With built-in Wi-Fi, it allows for viewing from any phone, tablet, or computer. The device easily attaches to a Welch Allyn retinoscope and could facilitate the teaching of retinoscopy for students, ophthalmic technicians, residents, and physicians.

Local Symmetry Breaking Suppresses Thermal Conductivity in Crystalline Solids.

Understanding the correlations of both the local and global structures with lattice dynamics is critical for achieving low lattice thermal conductivity (κ ) in crystalline materials. Herein, we demonstrate local cationic off-centring within the global rock-salt structure of AgSbSe by using synchrotron X-ray pair distribution function analysis and unravel the origin of its ultralow κ ≈0.4 W mK at 300 K.

Enhanced atomic ordering leads to high thermoelectric performance in AgSbTe.

High thermoelectric performance is generally achieved through either electronic structure modulations or phonon scattering enhancements, which often counteract each other. A leap in performance requires innovative strategies that simultaneously optimize electronic and phonon transports. We demonstrate high thermoelectric performance with a near room-temperature figure of merit, ~ 1.

The Pediatric Examination Assessment Rubric (PEAR) toolkit: reliability study.

Background: The Pediatric Examination Assessment Rubric (PEAR) toolkit consists of an examination sheet and rubric designed to assess ophthalmology residents' performance on the pediatric eye examination. The purpose of this study was to evaluate the reliability of the PEAR toolkit.

Methods: Six ophthalmology residents (2 PGY-2, 4 PGY-3) at a single ACGME-accredited US program participated in 11 video-recorded pediatric ophthalmology patient encounters.

Intrinsically Ultralow Thermal Conductivity in Ruddlesden-Popper 2D Perovskite CsPbICl: Localized Anharmonic Vibrations and Dynamic Octahedral Distortions.

Fundamental understanding of the correlation between chemical bonding and lattice dynamics in intrinsically low thermal conductive crystalline solids is important to thermoelectrics, thermal barrier coating, and more recently to photovoltaics. Two-dimensional (2D) layered halide perovskites have recently attracted widespread attention in optoelectronics and solar cells. Here, we discover intrinsically ultralow lattice thermal conductivity (κ) in the single crystal of all-inorganic layered Ruddlesden-Popper (RP) perovskite, CsPbICl, synthesized by the Bridgman method.

Identification of novel Urotensin-II receptor antagonists with potent inhibition of U-II induced pressor response in mice.

Urotensin II (U-II) has been found to be one of the most potent vasoconstrictor (Ames et al., 1999; Bohm et al., 2002) reported till date.

Intense versus standard regimens of intermittent occlusion therapy for unilateral moderate amblyopia in children: study protocol for a randomized controlled trial.

Background: We reported that in our previous study that wearing intermittent occlusion therapy glasses (IO-therapy) for 4 hours (h) was non-inferior to patching for 2 h in 3 to 8-year-old children with amblyopia. We hypothesize that an intense regimen of 12-h IO-therapy per day for 4 weeks could be as effective as the standard regimen of 4-h IO-therapy per day for 12 weeks in treating moderate amblyopia in 3 to 8-year-old children.

Methods/design: A total of 56 children between 3 and 8 years of age with amblyopia in association with anisometropia and/or strabismus will be enrolled.

Ultralow Thermal Conductivity in Chain-like TlSe Due to Inherent Tl Rattling.

Understanding the mechanism that correlates phonon transport with chemical bonding and solid-state structure is the key to envisage and develop materials with ultralow thermal conductivity, which are essential for efficient thermoelectrics and thermal barrier coatings. We synthesized thallium selenide (TlSe), which is comprised of intertwined stiff and weakly bonded substructures and exhibits intrinsically ultralow lattice thermal conductivity (κ) of 0.62-0.

Association of ABO blood types and novel obesity markers in healthy adolescents.

Introduction: Association of ABO blood type with body mass index (BMI) was explored in the past studies, but literature on association of novel obesity markerssuch as total body fat and lean body mass (LBM) is scarce. The present study aimed to evaluate the relationship of ABO blood types with novel obesity markers in normal adolescents.

Materials And Methods: A cross-sectional study was done on 387 medical students.

Feasibility of monitoring compliance with intermittent occlusion therapy glasses for amblyopia treatment.

Background: Liquid crystal glasses use an intermittent occlusion technique and may improve compliance compared to adhesive patches. Previous studies support the effectiveness of intermittent occlusion therapy (IO therapy) glasses for amblyopia treatment. However, objective compliance for these glasses has not been measured.

Susceptibility-weighted imaging of retinal hemorrhages in abusive head trauma.

Background: Retinal hemorrhages are one of the most important supportive evidences for abusive head trauma (AHT). Susceptibility-weighted imaging (SWI) is highly suited to identify various forms of intracranial hemorrhage in AHT. However its utility in imaging retinal hemorrhage is not well established.