Synopsis of recent research by authors named "Ajay Singh Tanwar"
- Ajay Singh Tanwar's research primarily focuses on the structural and functional analysis of enzymes, particularly those involved in nucleic acid metabolism and purine biosynthesis, revealing key insights into their mechanisms and regulatory features
- Notable findings include the cryo-electron microscopy structure of Fanzor2, which provides a new understanding of RNA-guided endonucleases, and the role of hydrophobic cavities in the allosteric regulation of formylglycinamide synthetase, elucidating the dynamic movements required for enzyme activation
- Tanwar has also identified the function of guanine deaminase from Nitrosomonas europaea, confirming its catalytic properties, and has explored the intricate coupling of reactive domains in formylglycinamide ribonucleotide amidotransferase, deepening our understanding of its multi-domain enzymatic functionality
