Spatial variability in residence time of Beryllium in the Indian Ocean.

Residence time of an element in the ocean is a consequence of its chemical behaviour and the various biogeochemical processes governing its distribution, sources, and sinks. Precise estimation of the residence time of beryllium(Be) is necessary for its application as a tracer for understanding present and paleo-environmental processes. We utilise cosmogenic Be and terrestrially derived Be measurements from surface sediments to estimate the residence time of Be in the Indian Ocean.

From Concept to Clinical Practice: A Review of Autotransplantation Techniques and Their Impact on Dentistry.

The goal of autotransplantation of teeth (ATT) is to provide the patient with a functioning tooth to replace a missing one. In dentistry, this surgery has gained significant approval and popularity; nonetheless, there is still a shortage of thorough evidence about its long-term effects. Tooth transplantation has a rich historical pedigree, and the main factors determining its success are the extra-alveolar period, proper splinting, periodontal ligament treatment, and root growth stage.

Optimizing Function and Aesthetics in Kennedy Class 1 Prosthetic Rehabilitation: A Case Report.

When dealing with a partially edentulous patient requiring rehabilitation for a distal extension, the situation becomes challenging if the patient is unwilling to consider placing implants or using a removable prosthesis. A patient with partial tooth loss may find it difficult to receive a satisfactory repair, especially if the missing teeth are at the back. The surrounding gum tissue and the underlying bone ridges provide support for dentures that encase natural teeth.

Development of a comprehensive cardiovascular disease genetic risk assessment test.

Background: Despite monogenic and polygenic contributions to cardiovascular disease (CVD), genetic testing is not widely adopted, and current tests are limited by the breadth of surveyed conditions and interpretation burden.

Methods: We developed a comprehensive clinical genome CVD test with semi-automated interpretation. Monogenic conditions and risk alleles were selected based on the strength of disease association and evidence for increased disease risk, respectively.

Foraging animal origin food samples as passive indicators of dioxin-like POPs contamination in industry sites: Method development, characterisation and risk assessment.

Titanium dioxide (TiO) is an important industrial chemical, and studies suggest its major production route - the chloride process could lead to the generation of unintentional dl-POPs. However, no relevant studies assessed the occurrence of dl-POPs associated with TiO production in the industrial zones, which is mostly due to the ultra-trace level distribution of these compounds in environmental compartments. The present study explored the novel possibility of utilising foraging animal-origin foods as sensitive indicators for addressing this challenge and generated a globally beneficial dataset by assessing the background levels of dl-POPs in the vicinity of a TiO production house in Southern India.

Dioxins emissions from bio-medical waste incineration: A systematic review on emission factors, inventories, trends and health risk studies.

COVID-19 has aggravated the biomedical waste generation all over the world and the concern for its safe disposal is on the rise. The vast majority of healthcare systems employ incineration as their treatment method considering its agility to reduce the waste volume by up to 95-96% and high-temperature inactivation of infectious biological materials. However, incinerator emission is a significant contributor of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and dioxin-like polychlorinated biphenyls (dl-PCBs) according to various national inventories across the globe.

Abandonment of fibreglass reinforced plastic fishing boats in Kerala, India, and chemical emissions arising from their burning.

Little information exists on the fate and impacts of boats constructed of fibreglass reinforced plastic (FRP) once they reach their end-of-life. In this study, the number of abandoned fishing boats constructed of FRP or constructed of plywood-wood and sheathed by FRP has been determined along the coast of Kerala, India, and chemical emissions have been estimated when boats are burned as a means of disposal. A total of 292 abandoned boats were observed across eight coastal transects constructed around selected landing centres, with abandonment ranging from 13 to 48 per km (average = 29 km).

Dioxin-like POPs emission trends as a decision support tool for developing sustainable MSW management scheme -an exploratory study.

The paper reports on an innovative application of dioxin-like persistent organic pollutants (dl-POPs) emission trends as a measure of environmental performance for designing feasible municipal solid waste management (MSWM) schemes. MSWM systems are highly dependent on the income status and the population density and it is quintessential for developing countries to devise strategies suiting to its characteristics rather than simply adapting successful processes/technologies in developed nations. Hence a lower-middle-income, high-density populated state of India - Kerala, which represents the typical scenario of majority of towns in developing countries was selected as the verification study site.

Garre's Sclerosing Chronic Osteomyelitis of Femur in an Adolescent.

Introduction: Garre's sclerosing osteomyelitis (GSO) is a rare chronic inflammatory disease resulting in thickening of cortices with loss of medullary canal without any signs of active infection.

Case Report: A 13-year-old boy presented in 2017 with the right thigh pain of 3 years duration, who had exhausted all conservative attempts. We operated the patient with intramedullary reaming with antibiotic-impregnated cement augmented Kuntscher nail, which got jammed.

Proposed city-specific interim targets for India based on WHO air quality guidelines 2021.

The World Health Organization has proposed the ambient air quality guidelines 2021. The uniqueness of the guidelines of the World Health Organization - air quality guidelines 2021 - is the inclusion of interim targets. Higher levels of air pollutants including PM for ambient air in India were recorded in recent times, and its association with respiratory and cardiovascular health risks was evidenced in the recent literature.

Rare Case of Undifferentiated Pleomorphic Sarcoma of the Right Parotid Gland Correlatively Demonstrated by F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and Contrast-Enhanced Magnetic Resonance Imaging.

Malignant fibrous histiocytoma (MFH)/undifferentiated pleomorphic sarcoma (UPS) is an uncommon malignancy in the head-and-neck region. UPS is a malignant neoplasm of uncertain origin that arises both in soft tissue and bone. We bring forth a 65-year-old female who presented with an ulceroproliferative growth in the right upper neck.

An experimental simulation study of conventional waste burning practices in India for the assessment and inventorisation of PCDD/F/dl-PCB emissions.

The paper reports an update to the polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (dl-PCBs) annual emission inventory of India from open burning of municipal solid wastes (MSW) through the generation of nation-specific emission factors for air (EF) and burned residue (EF) vectors. The MSW characteristics and modes of disposal practiced in Indian cities exhibits subtle variations from that of developed nations due to differences in food habits, living standards and climatic conditions. The annual emission calculations based on EFs from hitherto studies simulating conditions prevailing in developed countries can lead to anomalous accounting of emission levels.

Be depositional flux variation in the central Indian Ocean during the last 43 ka.

The advent of Accelerator Mass Spectrometer (AMS) enhanced the application of meteoric Be (half-life of 1.39 Ma) as a tracer for understanding earth surface processes on thousand to million-year time scales. However, for the majority of applications, an adequate understanding of the Be depositional flux is a prerequisite.

Biomass as source for hydrochar and biochar production to recover phosphates from wastewater: A review on challenges, commercialization, and future perspectives.

Excessive phosphate run-off with total phosphorus concentration greater than 20 μg P L triggers the growth of harmful algal species in waterbodies and potentially leads to eutrophication. This has severe negative implications on aquatic environment and impacts human health. The annual economic impact of harmful algal blooms is reported to be as high as $25 million for public health and commercial fishery sector, $29 million for recreation/tourism sector and $2 million for monitoring and management.

Intraperitoneal Urinary Bladder Rupture as a Cause of Pneumoperitoneum.

The most common cause of pneumoperitoneum in trauma patients is hollow viscus injury; however, in patients with pneumoperitoneum on imaging and normal hollow viscus during the laparotomy, other rare causes of pneumoperitoneum like intraperitoneal urinary bladder rupture should be ruled out. Urinary bladder can rupture either extraperitoneally or intraperitoneally or both. Rupture of the urinary bladder is commonly seen in patients with abdominal trauma; however, pneumoperitoneum is usually not seen in patients with traumatic bladder rupture.

First report of the infectious spleen and kidney necrosis virus (ISKNV) infection in ornamental fishes in India.

Infectious spleen and kidney necrosis virus (ISKNV), a member of family iridoviridae, reported for the first time in a wide range of ornamental fish species in India. Significant mortalities during the year 2018-19 were reported from a number of retailers in the region with various clinical signs. The samples of moribund, dead and apparently healthy ornamental fishes were collected from retailers, located in three districts of Karnataka, India.

Cellular Therapy: Shafts of Light Emerging for COVID-19.

The COVID-19 pandemic has presented with debilitating respiratory consequences especially more pronounced in high risk individuals. Individuals with underlying systemic diseases are more prone and vulnerable to suffer severe consequences of SARS-CoV-2 infectivity. The pathophysiological changes identified cytokine storm mechanism for out setting the series of adverse clinical conditions.

A novel ex-situ bio-remediation process for perchlorate contaminated soil.

A novel, ex-situ remediation process for perchlorate contaminated soil is reported in this study. This approach comprises washing the contaminated soil with water, followed by treatment of the wash water in a bioreactor. The treated water reused for the next batch of soil, and the cycle continued.

Clinical whole genome sequencing as a first-tier test at a resource-limited dysmorphology clinic in Mexico.

Patients with rare, undiagnosed, or genetic disease (RUGD) often undergo years of serial testing, commonly referred to as the "diagnostic odyssey". Patients in resource-limited areas face even greater challenges-a definitive diagnosis may never be reached due to difficulties in gaining access to clinicians, appropriate specialists, and diagnostic testing. Here, we report on a collaboration of the Illumina iHope Program with the Foundation for the Children of the Californias and Hospital Infantil de Las Californias, to enable deployment of clinical whole genome sequencing (cWGS) as first-tier test in a resource-limited dysmorphology clinic in northern Mexico.

A cross sectional study to assess the Tuberculosis Treatment Providers in the mid hills of India.

Background: A high level of knowledge about Tuberculosis amongst the Multi-Purpose Workers (MPWs) is the cornerstone for the successful implementation of Directly Observed Treatment Short-course (DOTS) strategy under the Revised National Tuberculosis control Programme of India. In this regard, the evaluation of MPWs, the major workforce of the Health Department of Solan district, has never been done in the past. Hence the present study was undertaken.

Copy-number variants in clinical genome sequencing: deployment and interpretation for rare and undiagnosed disease.

Purpose: Current diagnostic testing for genetic disorders involves serial use of specialized assays spanning multiple technologies. In principle, genome sequencing (GS) can detect all genomic pathogenic variant types on a single platform. Here we evaluate copy-number variant (CNV) calling as part of a clinically accredited GS test.

Trajectories of positive aspects of caregiving among family caregivers of stroke-survivors: the differential impact of stroke-survivor disability.

Objective To delineate positive aspects of caregiving trajectories among family caregivers of stroke-survivors and determine the impact of stroke-survivor disability, a time-varying factor, on the delineated trajectories. Methods In a longitudinal study, family caregivers of 173 stroke-survivors in Singapore were administered the Positive Aspects of Caregiving scale (PAC scale) thrice (baseline/3 months/6 months). Group-based trajectory modeling delineated positive aspects of caregiving trajectories and identified the impact of stroke-survivor disability on the trajectories.