Publications by authors named "Ajay Prasad"

The cycling of next-generation, high-capacity silicon (Si) anodes capable of 3579 mAh·g is greatly hindered by the instability of the solid-electrolyte interphase (SEI). The large volume changes of Si during (de)lithiation cause continuous cracking of the SEI and its reconstruction, leading to loss of lithium inventory and extensive consumption of electrolyte. The SEI formed in situ during cell cycling is mostly composed of molecular fragments and oligomers, the structure of which is difficult to tailor.

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  • Tuberculous peritonitis and peritoneal carcinomatosis are difficult to distinguish due to similar symptoms and insidious onset, but CT scans are essential for evaluation.
  • A study analyzed 44 tuberculous peritonitis cases and 45 peritoneal carcinomatosis cases to find distinguishing clinical and radiological features.
  • Key symptoms for tuberculous peritonitis included fever and weight loss, while abdominal pain and malignancy history were common in peritoneal carcinomatosis; specific imaging findings can help improve diagnosis.
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  • Autoimmune diseases, like rheumatoid arthritis and psoriasis, are becoming more common, and stress might make them worse or better.
  • Scientists tested how stress affects these diseases using rats, by exposing them to different stressors for 8 weeks.
  • The study found that stress increased inflammation and made arthritis and psoriasis worse in rats, showing that stress can have a big impact on these diseases.
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Rapid technological advancements are altering people's communication styles. With the growth of the Internet, social networks (Twitter, Facebook, Telegram, and Instagram) have become popular forums for people to share their thoughts, psychological behavior, and emotions. Psychological analysis analyzes text and extracts facts, features, and important information from the opinions of users.

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The Coronavirus Disease 2019 (COVID-19) outbreak has a devastating impact on health and the economy globally, that's why it is critical to diagnose positive cases rapidly. Currently, the most effective test to detect COVID-19 is Reverse Transcription-polymerase chain reaction (RT-PCR) which is time-consuming, expensive and sometimes not accurate. It is found in many studies that, radiology seems promising by extracting features from X-rays.

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The world is presently struggling with coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A patient with COVID-19 typically presents with fever, non-productive cough, dyspnea, and myalgia. A 49-year-old female presented with complaints of subacute onset and progressive symmetrical proximal muscle weakness of both upper limbs and lower limbs with no sensory, cranial nerve deficit.

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Background: A pandemic poses a significant challenge to the healthcare staff and infrastructure. We studied the prevalence of anxiety and depressive symptoms among armed forces doctors in India during the COVID-19 pandemic and the factors that contribute to these symptoms.

Methods: The study was conducted from March 30, 2020, to April 2, 2020, using a self-administered questionnaire questionnaire using the hospital anxiety and depression scale (HADS), which was sent through Google Forms.

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Background: A prospective study was conducted during the second phase of the coronavirus disease 2019 (COVID-19) pandemic in India to assess the prevalence of anxiety and depressive symptoms among healthcare workers (HCWs) and factors that influence the outcome.

Methods: A self-administered questionnaire was completed by 1124 HCWs during the COVID-19 pandemic (March 30, 2020, to April 2, 2020). Demographic data, questions on COVID-19 and scores of the Hospital Anxiety and Depression Scale were analysed using the chi-square test (Bonferroni correction) and binary logistic regression.

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Aggregation and the formation of oligomeric intermediates of amyloid-β (Aβ) at the membrane interface of neuronal cells are implicated in the cellular toxicity and pathology of Alzheimer's disease. Small molecule compounds have been shown to suppress amyloid aggregation and cellular toxicity, but often the presence of a lipid membrane negates their activity. A high-throughput screen of 1800 small molecules was performed to search for membrane active inhibitors, and 21 primary hits were discovered.

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Energy is associated with anything and everything around us and can be transferred, transformed but cannot be destroyed. Many existing theories in physics like quantum physics, metaphysics, and electromagnetism give rise to the thought for the existence of an invisible field of bio-energy, in living things. Every living being, at its atomic level, absorbs and releases a good amount of energy, which is not visible through normal eyes but observable to measure through other means.

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Proton conductivity of the polymer electrolyte membranes in fuel cells dictates their performance and requires sufficient water management. Here, we report a simple, scalable method to produce well-dispersed transition metal carbide nanoparticles. We demonstrate that these, when added as an additive to the proton exchange Nafion membrane, provide significant enhancement in power density and durability over 100 hours, surpassing both the baseline Nafion and platinum-containing recast Nafion membranes.

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Background: Predicting molecular responses in human by extrapolating results from model organisms requires a precise understanding of the architecture and regulation of biological mechanisms across species.

Results: Here, we present a large-scale comparative analysis of organ and tissue transcriptomes involving the three mammalian species human, mouse and rat. To this end, we created a unique, highly standardized compendium of tissue expression.

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The human lung comprises about 300 million alveoli which are located on bronchioles between the 17th to 24th generations of the acinar tree, with a progressively higher population density in the deeper branches (lower acini). The alveolar size and aspect ratio change with generation number. Due to successive bifurcation, the flow velocity magnitude also decreases as the bronchiole diameter decreases from the upper to lower acini.

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The acinar region of the human lung comprises about 300x10(6) alveoli, which are responsible for gas exchange between the lung and the blood. As discussed in Part I (Chhabra and Prasad, "Flow and Particle Dispersion in a Pulmonary Alveolus-Part I: Velocity Measurements and Convective Particle Transport," ASME J. Biomech.

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The alveoli are the smallest units of the lung that participate in gas exchange. Although gas transport is governed primarily by diffusion due to the small length scales associated with the acinar region (approximately 500 microm), the transport and deposition of inhaled aerosol particles are influenced by convective airflow patterns. Therefore, understanding alveolar fluid flow and mixing is a necessary first step toward predicting aerosol transport and deposition in the human acinar region.

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The adverse health effects of inhaled particulate matter from the environment depend on its dispersion, transport, and deposition in the human airways. Similarly, precise targeting of deposition sites by pulmonary drug delivery systems also relies on characterizing the dispersion and transport of therapeutic aerosols in the respiratory tract. A variety of mechanisms may contribute to convective dispersion in the lung; simple axial streaming, augmented dispersion, and steady streaming are investigated in this effort.

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An understanding of flow and dispersion in the human respiratory airways is necessary to assess the toxicological impact of inhaled particulate matter as well as to optimize the design of inhalable pharmaceutical aerosols and their delivery systems. Secondary flows affect dispersion in the lung by mixing solute in the lumen cross section. The goal of this study is to measure and interpret these secondary velocity fields using in vitro lung models.

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