Publications by authors named "Ajay P Desai"

Article Synopsis
  • Maxillofacial reconstruction is complicated due to the region's intricate anatomy and its impact on patients' functionality and appearance.
  • Emerging technologies enable the use of patient-specific implants (PSIs) through virtual surgical planning, enhancing treatment options for those with maxillofacial defects and facilitating surgeries like orthognathic procedures.
  • While autogenous tissue remains the gold standard for reconstruction, PSIs reduce complications associated with donor sites, and future research aims to utilize PSIs as scaffolds for tissue engineering to restore lost anatomy.
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Article Synopsis
  • Plasmablastic lymphoma (PBL) is a rare and aggressive type of large B-cell lymphoma often found in HIV-positive patients, commonly appearing in the oral cavity but not frequently reported as such in medical literature.
  • Oral PBL typically manifests as asymptomatic swelling with ulcerations and bleeding, and there is no established treatment protocol for this condition, resulting in a low five-year survival rate of around 33.5%.
  • The case presented highlights the importance of recognizing oral lesions as potential indicators of serious underlying health issues, as a suspicious ulcerated growth in the upper jaw was ultimately diagnosed as a rare HIV-related lymphoma rather than carcinoma.
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Carotid- Cavernous Fistula (CCF) represents an aberrant vascular communication at the skull base between the high-flow carotid arterial system and the low-flow venous channels within the cavernous sinuses of the sphenoid bone. Benjamin Travers, in the year 1809, described this condition as "pulsating exophthalmos". This case is a presentation of a carotid cavernous fistula in an operated case of maxillofacial injury as a late complication.

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Purpose: The aim of this clinical study was to evaluate the level of Interleukine-6 (IL-6), pre and post arthrocentesis to validate it as a biomarker in the Internal Derangement (ID) of TMJ.

Material And Methods: This study included 30 patients (20 females and 10 males) of Temporo-Mandibular Dysfunction (TMD) with Disc displacement without reduction (DDwoR) Wilkes stage III, who were refractory to conservative management. Arthrocentesis was performed as a therapeutic modality.

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Background: Stomatognathic system is an interaction of the muscles of mastication, dentition, neural component, and temporomandibular joint. Any dysfunction in this system may lead to temporomandibular disorders (TMDs). Various non-surgical modalities have been employed for treating TMDs.

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Background: Platelet-rich plasma (PRP) has been a breakthrough in the stimulation and acceleration of bone and soft tissue healing. It represents a relatively new biotechnology that is part of the growing interest in tissue engineering and cellular therapy.

Methods: A prospective study was carried out in 50 patients.

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Penetrating facial injuries are potentially dangerous and may require emergency management because of the presence of vital structures in the face, and it may be life-threatening especially when the injury involves airway, major blood vessels, spinal cord, and cervical spines. Penetrating injuries of the facial region can occur due to missile injuries, blast injuries, motor vehicle accidents, and accidental fall on sharp objects. However, injury to face caused by the shattering of a protective helmet itself is extremely rare.

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Breach in the palatal vault leading to an abnormal communication between oral and nasal cavity is known as oro-nasal communication. It is an uncommon presentation in day-to-day clinical practice except in some patients of cleft lip and palate.Etiology may be congenital or acquired.

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Article Synopsis
  • The study assesses the use of strip craniectomy paired with distraction osteogenesis for treating craniosynostosis in two selected cases.
  • After a delay of 4 days, distraction was executed using intraoral devices, achieving 25-28 mm separation of the skull segments.
  • Results showed increased skull size, enhanced cognitive function, and reduced symptoms associated with elevated intracranial pressure, indicating that this combined treatment is effective.
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Objective: The aim of the study was to cephalometrically evaluate hard and soft tissue changes in cases of cleft-induced maxillary hypoplasia treated by distraction osteogenesis using rigid external distractor (RED).

Methods: Fifteen cases of cleft-induced maxillary hypoplasia were selected applying the inclusion and exclusion criteria. The cases were operated on under general anesthesia for distraction osteogenesis using RED.

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Objective: To do a comparative study and evaluate the outcome in healing of reconstructed cranial defects with an autogenous bone graft vis-à-vis alloplastic materials.

Methods: A total of 22 patients with cranial defects were selected for this study. All the subjects were men; mean age was 27 years.

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