Impact of Ionic Liquids on the Physicochemical Behavior of Vesicles.

The effects of two ionic liquids (ILs), 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF) and 1-butyl-1-methyl pyrrolidinium tetrafluoroborate ([bmp]BF), on a mixture of phospholipids (PLs) 1,2-dipalmitoyl--glycero-3-phosphatidylcholine (DPPC), 1,2-dipalmitoyl--glycero-3-phosphoethanolamine (DPPE), and 1,2-dipalmitoyl--glycero-3-phosphoglycerol (DPPG) (6:3:1, M/M/M, 70% PL) in combination with 30 mol % cholesterol (CHOL) were investigated in the form of a solvent-spread monolayer and bilayer (vesicle). Surface pressure (π)-area () isotherm studies, using a Langmuir surface balance, revealed the formation of an expanded monolayer, while the cationic moiety of the IL molecules could electrostatically and hydrophobically bind to the PLs on the palisade layer. Turbidity, dynamic light scattering (size, ζ-potential, and polydispersity index), electron microscopy, small-angle X-ray/neutron scattering, fluorescence spectroscopy, and differential scanning calorimetric studies were carried out to evaluate the effects of IL on the structural organization of bilayer in the vesicles.

A fluorescence based dual sensor for Zn and PO and the application of soft computing methods to predict machine learning outcomes.

A phenolphthalein-based Schiff base, 3,3-bis-{4-hydroxy-3-[(pyridine-2-ylmethylimino)-methyl]-phenyl}-3-isobenzofuran-1-one (PAP), has been synthesized and used for selective fluorescence 'turn on' and 'turn off' sensing of Zn and PO respectively. The limit of detection using the 3 method for Zn is found to be 19.3 nM and that for PO is 8.

Effect of charge transfer on the first hyper-polarizability of N,N-dimethylaniline and julolidine: a DFT based comparative study.

Context: Quantum mechanical calculations involving electron correlation, frequency dispersion, and solvent effects were carried out to examine the second-order nonlinear optical response of various acceptor, X (-CF, -CN, -NO) substituted in N,N-dimethylaniline (DMA) and julolidine(JLD). Here, both DMA and JLD acts as donor and the three substituted groups, X (-CF, -CN and -NO) at the para position of both the ring systems as acceptor. The NLO response (βHRS) of -CF and -CN substituted DMA and JLD is relatively lower compared to DMA-NO and JLD-NO.

Synthesis of Fluorophore Based Functional Material for Selective Detection of Al Ion in Water and Decoding the AIEE Property of Its Hydrosol.

A designed aggregation-induced emission enhancement (AIEE) active fluorescence probe 2,3-Bis-[(2-hydroxy-napthalen-1-ylmethylene)-amino]-but-2-enedinitrile (L) was synthesized via one step condensation method. The probe shows swift sensitivity and selectivity toward Alover other relevant metal ions and also exhibits significant AIEE phenomena in methanol/water mixture. Significant enhancement of fluorescence intensity is triggered via chelation-enhanced fluorescence through complex (Al-L) formation.

Anthracene scaffold as highly selective chemosensor for Al and its AIEE activity.

Fluorescent chemosensor, 3-(Anthracen-2-yliminomethyl)-benzene-1,2-diol (ANB) has been synthesized by one-step condensation of 2-aminoanthracene and 2,3-dihydroxybenzaldehyde and characterized using H-NMR, FT-IR and Mass spectroscopic techniques. The probe ANB was found to be an efficient 'turn-on' fluorescence chemosensor for the selective detection of Al ion over other metal ions in an aqueous solution. The chemosensor exhibits ~ 27-fold enhancement of emission intensity in presence of Al ion.

Fluorescence 'Turn-on' Dual Sensor for Selective Detection of Cd and HAsO in Water.

A multi responsive fluorescent probe, N',2-bis(E-4-(diethylamino)-2-hydroxybenzylidene)hydrazine-1-carbothiohydrazideV(HL) has been synthesized through one step condensation method. Probe, HL shows 'turn-on' dual sensing properties towards Cd and HAsO at two distinct wavelength. The probe (HL) is spectroscopically characterized and the chemo-sensing mechanism has been demonstrated through H NMR, absorption, steady state and time resolved emission study.

Highly Sensitive 'on-off' Pyrene Based AIEgen for Selective Sensing of Copper (II) Ions in Aqueous Media.

A Fluorescent chemosensor based on pyrene scaffold, 5-diethylamino-2-(pyren-1-yliminomethyl)-phenol (PDS) is synthesized using condensation method. It displays novel aggregation-induced emission (AIE) phenomena in its aggregated/solid state. The AIE characteristic of PDS is studied in CHCN/HO mixtures at different volume percentage of water and morphology of the aggregated particles are investigated by DLS and optical fluorescence microscopic study.

A bio-compatible pyridine-pyrazole hydrazide based compartmental receptor for Al sensing and its application in cell imaging.

For practical applications, the development of bio-compatible organic molecules as p-block ion chemosensors is critical. Herein, we report the single crystal (SC) of new pyridine-pyrazole derived Al sensor H2PPC [()-'-(2,3-dihydroxybenzylidene)-5-methyl-1-(pyridin-2-yl)-1-pyrazole-3-carbohydrazide] as well as its Cu-complex SC. The probe exhibits an "off-on" fluorescence response towards Al ions, and this has been modulated with different solvents.

Acetate ion augmented fluorescence sensing of Zn by Salen-based probe, AIE character, and application for picric acid detection.

Counter anion-triggered metal ion detection has been rarely reported by fluorimetric method. To address this challenging issue, a fluorescent probe () has been synthesized from bromo-salicylaldehyde and hydrazine hydrate, and structurally characterized by single crystal X-ray diffraction. The probe shows very weak fluorescence itself.

Solvent-Regulated Fluorimetric Differentiation of Al and Zn Using an AIE-Active Single Sensor.

The absence of d-orbital electrons or presence of full-filled d-orbital electrons in metal ions is a well-known Achilles' heel problem for the detection of these metal ions by a simple UV-visible study. For this reason, detection of metal ions such as Al with no d-orbital electrons or Zn with filled d-orbital electrons is a challenging task. Herein, we report a 2-naphthol-based fluorescent probe [1-(()-(()-(5-bromo-2-hydroxybenzylidene)hydrazono)methyl)naphthalen-2-ol] () that has been used to sense and discriminate Al and Zn via solvent regulation.

Designed Synthesis of Fluorescence 'Turn-on' Dual Sensor for Selective Detection of Al and Zn in Water.

1-(Pyridin-2-yl-hydrazonomethyl)-naphthalen-2-ol (PNOH) is a naphthalene-based fluorescence dual chemo-sensor for Al and Zn. The probe (PNOH) is spectroscopically characterised and the chemo-sensing mechanism has been demonstrated through H NMR, absorption and both steady state and time resolved fluorescence study. The 'turn-on' luminescence property of PNOH is used for the selective detection of trace amount of Aland Znvia chelation enhanced fluorescence (CHEF) through complex formation.

An antipyrine based fluorescent probe for distinct detection of Al and Zn and its AIEE behaviour.

A simple antipyrine based fluorescent probe, 4-[(2-hydroxy-3-methoxy-benzylidene)-amino]-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one (OVAP), has been successfully synthesized using a one-step condensation method. It exhibits dual sensing properties toward Al3+ and Zn2+ in the presence of other relevant metal ions and also displays novel aggregation induced emission enhancement (AIEE) characteristics in its aggregated/solid state. Aggregated OVAP microstructures with interesting morphologies have been synthesized using SDS as a morphology directing agent.

An antipyrine based fluorescence "turn-on" dual sensor for Zn and Al and its selective fluorescence "turn-off" sensing towards 2,4,6-trinitrophenol (TNP) in the aggregated state.

A 2,6-diformyl-p-cresol (DFC)-4-amino antipyrine (AP) based dual signaling fluorescent Schiff base ligand (DFCAP) is found to exhibit colorimetric and fluorescence turn on selective sensing towards metal ions, Zn2+ and Al3+. It also exhibits a significant aggregation induced emission (AIE) phenomenon by controlling the water-THF solvent ratio which provides robust green emissive fluorogenic aggregates with well-defined morphologies. Turn-on fluorescence enhancements as high as 195 fold and 168 fold in methanol for Al3+ and Zn2+ at 480 nm and 508 nm, respectively, were noticed.

Rhodamine scaffolds as real time chemosensors for selective detection of bisulfite in aqueous medium.

Rhodamine and its derivatives have been widely used in designing fluorescent 'turn on' cation sensors, while very few rhodamine based fluorescent probes have been reported to date for the detection of anions in water. In this article, a new rhodamine based facile and convenient 'turn on' fluorescent chemosensor 2-(2-(1-hydroxynaphthyllideneamino)ethyl)-3',6'-bis(diethylamino)spiro [isoindoline-1,9'-xanthen]-3-one (RAHN) has been developed by Schiff base condensation and characterized by standard techniques for selective detection of bisulfite anions in water. A faintly yellow colour solution of RAHN turns pink upon addition of bisulfite.

Paraquat poisoning: Case report of a survivor.

N, N'-dimethyl-4, 4'-bipyridinium dichloride (paraquat) is a widely used synthetic, nonselective contact herbicide. Ingestion of toxic doses of paraquat can be fatal with life-threatening effects on the lungs, gastrointestinal (GI) tract, kidney, liver, heart, and other organs. Till date, there are no specific antidotes and none of the current treatments have proven efficacious.

Aggregation induced emission from α-napthoflavone microstructures and its cyto-toxicity.

α-Napthoflavone (ANF) microstructures of various morphologies were synthesized using reprecipitation method. Sodium Dodecyl Sulfate (SDS) was used as morphology directing agent. The morphologies of the particles were characterized using optical and scanning electron microscopy (SEM).

Crystal induced phosphorescence from Benz(a)anthracene microcrystals at room temperature.

Pure organic compounds that are also phosphorescent at room temperature are very rare in literature. Here, we report efficient phosphorescence emission from aggregated hydrosol of Benz(a)anthracene (BaA) at room temperature. Aggregated hydrosol of BaA has been synthesized by re-precipitation method and SDS is used as morphology directing agent.

Pyrene Scaffold as Real-Time Fluorescent Turn-on Chemosensor for Selective Detection of Trace-Level Al(III) and Its Aggregation-Induced Emission Enhancement.

A pyrene based fluorescent probe, 3-methoxy-2-((pyren-2yl-imino)methyl)phenol (HL), was synthesized via simple one-pot reaction from inexpensive reagents. It exhibited high sensitivity and selectivity toward Al(3+) over other relevant metal ions and also displayed novel aggregation-induced emission enhancement (AIEE) characteristics in its aggregate/solid state. When bound with Al(3+) in 1:1 mode, a significant fluorescence enhancement with a turn-on ratio of over ∼200-fold was triggered via chelation-enhanced fluorescence through sensor complex (Al-L) formation, and amusingly excess addition of Al(3+), dramatic enhancement of fluorescence intensity over manifold through aggregate formation was observed.

Proton triggered emission and selective sensing of picric acid by the fluorescent aggregates of 6,7-dimethyl-2,3-bis-(2-pyridyl)-quinoxaline.

A heteroatom containing organic fluorophore 6,7-dimethyl-2,3-bis-(2-pyridyl)-quinoxaline (BPQ) is weakly emissive in solution but its emission properties are highly enhanced in the aggregated state due to the restriction of intramolecular rotation (RIR) and large amplitude vibrational modes, demonstrating the phenomenon, aggregation induced emission enhancement (AIEE). It has strong proton capture capability, allowing reversible fluorescence switching in basic and acidic medium and the emission color changes from blue to green in the aggregated state through protonation. It has been explained as a competition between intramolecular charge transfers (ICTs) and the AIEE phenomena at a lower pH range (pH ∼1-4).

Aggregation induced emission enhancement of 4,4'-bis(diethylamino)benzophenone with an exceptionally large blue shift and its potential use as glucose sensor.

Optical emission from a luminogen in solid state is generally red shifted with respect to its solution phase emission. However, in our present study, we report exceptionally large blue shifted enhanced emission from aggregated hydrosol of 4,4'-bis(diethylamino)benzophenone (BZP) compared to its solution phase emission in any good solvent. This exceptional blue emission from aggregated structure of BZP arises from its locally excited states with the concomitant suppression of twisted intramolecular charge transfer (TICT) motion.

Aggregation induced emission enhancement from Bathophenanthroline microstructures and its potential use as sensor of mercury ions in water.

Bathophenanthroline (BA) microstructures of various morphologies have been synthesized using a reprecipitation method. The morphologies of the particles are characterized using optical and scanning electron microscopy (SEM) methods. An aqueous dispersion of BA microstructures shows aggregation induced emission enhancement (AIEE) compared to BA in a good solvent, THF.

Synthesis of worm like silver nanoparticles in methyl cellulose polymeric matrix and its catalytic activity.

A facile one step method for the synthesis of wormlike silver nanoparticles has been carried out in methyl cellulose matrix. Synthesis is based on the reduction of AgNO3 by sodium borohydride (NaBH4) in aqueous methyl cellulose (MC). Synthesized nanoparticles are mostly mono disperse in size and their aggregation is controlled by varying the concentration of AgNO3.

Enhanced photocatalytic activity of metal coated ZnO nanowires.

A simple, facile and template free route has been described for the synthesis of ZnO nanowires. The morphology and structure of ZnO nanowires have been tuned by deposing silver and gold onto the surface of ZnO nanowire and this has been done by adding AgNO(3) and HAuCl(4) to aqueous suspension of ZnO. Our synthesized Ag and Au coated ZnO nanoparticles show different emissive property than the native ZnO nanowires.