Publications by authors named "Ajay Madhaven"
Background: Some patients with progressive supranuclear palsy syndrome (PSPS) demonstrate a focal area of midbrain hypometabolism on FDG-PET scans which we call the 'pimple sign'. We assessed its association with midbrain atrophy, its reliability and its ability to differentiate PSPS from corticobasal syndrome (CBS) and multiple system atrophy (MSA).
Methods: We identified 67 patients with PSPS, CBS or MSA who had volumetric MRI as well as FDG-PET imaging.