Publications by authors named "Ajay Chaurasia"

Article Synopsis
  • Glaucoma is a major cause of vision loss globally, highlighting the need for early detection, which this research addresses by using deep learning for automated diagnosis through retinal fundus photos.* -
  • The study introduces a new optic nerve head feature from OCT images and a deep learning classifier that can quickly differentiate between normal and abnormal eyes without manual input, improving the diagnostic process.* -
  • A new mixed loss function enhances the model's ability to deal with complex data and class imbalances, achieving outstanding accuracy (100%), specificity (99.8%), and sensitivity (99.2%), showcasing its potential for effective clinical application in glaucoma detection.*
View Article and Find Full Text PDF

Context: Coronary artery perforation is a rare but potentially catastrophic complication of percutaneous coronary intervention (PCI). It is infrequent complication of PCI.

Aims: The objective of the study is to report the 7-year experience of coronary artery perforation with respect to incidence, clinical and angiographic characteristics, management and outcomes.

View Article and Find Full Text PDF

Objective: To determine prevalence of methylenetetrahydrofolate reductase (MTHFR) mutations in apparently healthy individuals residing in Mumbai and patients with deep vein thrombosis (DVT) and coronary artery disease (CAD) and to correlate these polymorphisms with homocysteine (Hcy) levels.

Materials And Methods: This case-control study was initiated after receiving ethical approval and following the participant's written consent. One hundred and twenty unmatched healthy volunteers and 240 patients with arterial and venous thrombosis were enrolled.

View Article and Find Full Text PDF

"Acute take off" of the left circumflex artery (LCX) is a rare coronary artery variant. Development of coronary artery disease in such a vessel increases technical difficulty and failure rate for percutaneous coronary intervention. We report a rare case of "acute take off" of the LCX with proximal critical stenosis successfully intervened using dual-lumen microcatheter.

View Article and Find Full Text PDF

Congenital coronary anomalies are rare and reported to occur in 0.64-1.3% of patients undergoing coronary angiography.

View Article and Find Full Text PDF

Implantation of temporary pacemaker lead is commonly performed procedure and is usually safe, but can sometimes develop rare and serious complication like intracardiac lead knotting which may require challenging retrieval techniques. We report a case of successful percutaneous retrieval of unusually knotted right internal jugular venous temporary pacing lead via left femoral transvenous approach using snare over a long sheath after cutting the electrode proximally and thus avoiding any surgical intervention.

View Article and Find Full Text PDF

Glioblastoma (GBM) can be classified into molecular subgroups, on the basis of biomarker expression. Here, we classified our cohort of 163 adult GBMs into molecular subgroups according to the expression of proteins encoded by genes of alpha thalassemia/mental retardation syndrome X-linked (ATRX), isocitrate dehydrogenase (IDH) and TP53. We focused on the survival rate of molecular subgroups, depending on each and various combination of these biomarkers.

View Article and Find Full Text PDF

Aim: Present study aims to study the occurrence of cirrhotic cardiomyopathy and its correlation to hepatorenal syndrome by assessing the cardiac status in patients with cirrhosis of liver and healthy controls.

Methods: Thirty alcoholic cirrhotic, thirty non-alcoholic cirrhotic and thirty controls were enrolled for the study. Cardiac parameters were assessed by color doppler echocardiography.

View Article and Find Full Text PDF

We describe a rare case of pulmonary valve endocarditis associated with a double-chambered right ventricle in an adolescent male highlighting the two-dimensional and three-dimensional transthoracic echocardiographic findings. He was managed with aggressive antibiotic therapy followed by surgery. The echocardiographic findings were confirmed during surgery.

View Article and Find Full Text PDF

Background: Electrocardiographic abnormalities mimicking myocardial ischemia have been reported in intra-abdominal conditions, including acute pancreatitis. However, the occurrence of ST-elevation myocardial infarction (STEMI) is rare.

Objectives: To present a case report of a young man with acute pancreatitis subsequently complicated by acute STEMI.

View Article and Find Full Text PDF

Percutaneous balloon tricuspid valvotomy was successfully performed in a 45-year-old female with congenitally corrected transposition of great arteries with severe rheumatic left atrioventricular (tricuspid) valve stenosis. Technical modifications in the standard procedure were made keeping in mind the left-handed ventricular loop, left and anterior aorta, wedged pulmonary valve between the interatrial septum and the mitral valve with deviation of the atrial septum away from the ventricular septum, side-by-side positioned ventricles with an added superoinferior obliquity produced by excessive tilting, and an abnormal orientation of ventricular mass in relation to the thorax, with the apex pointing slightly rightwards. A final valve area of 1.

View Article and Find Full Text PDF